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Stock-Based Compensation (Tables)
9 Months Ended
Sep. 30, 2018
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]  
Schedule of stock-based compensation expense
Stock-based compensation expense is included in the consolidated statements of operations as follows (in thousands):
 
Three Months Ended September 30,
 
Nine Months Ended September 30,
 
2018
 
2017
 
2018
 
2017
Research and development
$
552

 
$
386

 
$
1,555

 
$
1,050

Selling, general and administrative
1,218

 
1,447

 
4,652

 
4,162

   Total
$
1,770

 
$
1,833

 
$
6,207

 
$
5,212

Schedule of stock-based compensation expense by security types
The following table presents total stock-based compensation expense by security types included in the unaudited condensed consolidated statements of operations for the three and nine months ended September 30, 2018 and 2017 (in thousands):
 
Three Months Ended September 30,
 
Nine Months Ended September 30,
 
2018
 
2017
 
2018
 
2017
Stock options
$
472

 
$
393

 
$
1,482

 
$
1,107

RSUs and RSAs
416

 
456

 
1,293

 
1,399

PSUs
407

 
385

 
1,251

 
1,373

PBOs
475

 
599

 
2,181

 
1,333

   Total
$
1,770

 
$
1,833

 
$
6,207

 
$
5,212

Valuation assumptions
The weighted-average assumptions used to estimate the fair value of employee stock options and PBOs granted were as follows:
 
Three Months Ended September 30,
 
Nine Months Ended September 30,
 
2018
 
2017
 
2018
 
2017
 
 
 
(1)
 
 
 
 
Expected term (in years)
5.7

 

 
5.6

 
5.3

Volatility
57
%
 

 
60
%
 
62
%
Risk-free interest rate
2.78
%
 

 
2.70
%
 
2.02
%
Dividend yield
%
 

 
%
 
%
Weighted-average estimated fair value of stock options granted
$
8.39

 

 
$
5.10

 
$
2.52


(1) The Company did not grant employee stock options or PBOs in the three months ended September 30, 2017.