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Stock-Based Compensation (Tables)
3 Months Ended
Mar. 31, 2018
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]  
Schedule of stock-based compensation expense
Stock-based compensation expense is included in the consolidated statements of operations as follows (in thousands):
 
Three Months Ended March 31,
 
2018
 
2017
Research and development
$
435

 
$
323

Selling, general and administrative
1,545

 
1,346

   Total
$
1,980

 
$
1,669

Schedule of stock-based compensation expense by security types
The following table presents total stock-based compensation expense by security types included in the unaudited condensed consolidated statements of operations for the three months ended March 31, 2018 and 2017 (in thousands):
 
Three Months Ended March 31,
 
2018
 
2017
Stock options
$
472

 
$
334

RSUs and RSAs
452

 
459

PSUs
409

 
641

PBOs
647

 
235

   Total
$
1,980

 
$
1,669

Valuation assumptions
The weighted-average assumptions used to estimate the fair value of employee stock options and PBOs granted were as follows:
 
Three Months Ended March 31,
 
2018
 
2017
Expected term (in years)
5.6

 
5.3

Volatility
60
%
 
62
%
Risk-free interest rate
2.70
%
 
2.00
%
Dividend yield

 
%
Weighted-average estimated fair value of stock options granted
$
5.02

 
$
2.52