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Balance Sheets Details (Intangible Assets, net) (Details) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2017
Dec. 31, 2016
Finite-Lived Intangible Assets [Line Items]    
Gross Carrying Amount $ 21,778 $ 21,778
Accumulated Amortization (21,778) (21,778)
Net Carrying Amount 0 0
Developed and core technology [Member]    
Finite-Lived Intangible Assets [Line Items]    
Gross Carrying Amount 1,534 1,534
Accumulated Amortization (1,534) (1,534)
Net Carrying Amount $ 0 0
Amortization Period (years) 5 years  
Maxygen intellectual property [Member]    
Finite-Lived Intangible Assets [Line Items]    
Gross Carrying Amount $ 20,244 20,244
Accumulated Amortization (20,244) (20,244)
Net Carrying Amount $ 0 $ 0
Amortization Period (years) 6 years