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Stock-Based Compensation (Tables)
3 Months Ended
Mar. 31, 2017
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]  
Schedule of stock-based compensation expense
Stock-based compensation expense is included in the consolidated statements of operations as follows (in thousands):
 
Three Months Ended March 31,
 
2017
 
2016
Research and development
$
323

 
$
220

Selling, general and administrative
1,346

 
1,169

   Total
$
1,669

 
$
1,389

Schedule of stock-based compensation expense by security types
The following table presents total stock-based compensation expense by security types included in the condensed consolidated statements of operations for the three months ended March 31, 2017 and 2016 (in thousands):
 
Three Months Ended March 31,
 
2017
 
2016
Stock options
$
334

 
$
304

RSUs and RSAs
459

 
574

PSUs
641

 
511

PBOs
235

 

   Total
$
1,669

 
$
1,389

Valuation assumptions
The weighted-average assumptions used to estimate the fair value of employee stock options and PBOs granted were as follows:
 
Three Months Ended March 31,
 
2017
 
2016
Expected term (in years)
5.3

 
5.4

Volatility
62
%
 
65
%
Risk-free interest rate
2.00
%
 
1.30
%
Dividend yield
%
 
%
Weighted-average estimated fair value of stock options granted
$
2.52

 
$
2.31