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Basis of Presentation and Summary of Significant Accounting Policies - Plant, Property, and Equipment (Details)
12 Months Ended
Dec. 31, 2016
Laboratory equipment  
Property, Plant and Equipment [Line Items]  
Estimated useful life (years) 5 years
Computer equipment and software | Minimum  
Property, Plant and Equipment [Line Items]  
Estimated useful life (years) 3 years
Computer equipment and software | Maximum  
Property, Plant and Equipment [Line Items]  
Estimated useful life (years) 5 years
Office equipment and furniture  
Property, Plant and Equipment [Line Items]  
Estimated useful life (years) 5 years