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Balance Sheets Details (Intangible Assets, net) (Details) - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2016
Dec. 31, 2015
Finite-Lived Intangible Assets [Line Items]    
Gross Carrying Amount $ 21,778 $ 21,778
Accumulated Amortization (21,497) (18,966)
Net Carrying Amount 281 2,812
2016 (remaining 3 months) 300  
Developed and core technology [Member]    
Finite-Lived Intangible Assets [Line Items]    
Gross Carrying Amount 1,534 1,534
Accumulated Amortization (1,534) (1,534)
Net Carrying Amount $ 0 0
Amortization Period (years) 5 years  
Maxygen Intellectual Property [Member]    
Finite-Lived Intangible Assets [Line Items]    
Gross Carrying Amount $ 20,244 20,244
Accumulated Amortization (19,963) (17,432)
Net Carrying Amount $ 281 $ 2,812
Amortization Period (years) 6 years