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Balance Sheets Details (Intangible Assets, net) (Details) - USD ($)
$ in Thousands
6 Months Ended
Jun. 30, 2016
Dec. 31, 2015
Finite-Lived Intangible Assets [Line Items]    
Gross Carrying Amount $ 21,778 $ 21,778
Accumulated Amortization (20,653) (18,966)
Net Carrying Amount 1,125 2,812
2016 (remaining 6 months) 1,125  
Developed and core technology [Member]    
Finite-Lived Intangible Assets [Line Items]    
Gross Carrying Amount 1,534 1,534
Accumulated Amortization (1,534) (1,534)
Net Carrying Amount $ 0 0
Amortization Period (years) 5 years  
Maxygen Intellectual Property [Member]    
Finite-Lived Intangible Assets [Line Items]    
Gross Carrying Amount $ 20,244 20,244
Accumulated Amortization (19,119) (17,432)
Net Carrying Amount $ 1,125 $ 2,812
Amortization Period (years) 6 years