Balance Sheets Details (Tables)

6 Months Ended

Jun. 30, 2014

Balance Sheets Details [Abstract]

Schedule of inventory components

Inventory, net consisted of the following (in thousands):

	June 30, 2014		December 31, 2013
Raw materials	$	452	$	763
Work in process	229		31
Finished goods	1,282		693
Inventory, net	$	1,963	$	1,487

Schedule of property and equipment, net

Property and equipment, net consisted of the following (in thousands):

	June 30, 2014				December 31, 2013
Laboratory equipment	$	23,774			$	23,949
Leasehold improvements	9,493				9,493
Computer equipment	3,249				3,196
Office furniture and equipment	1,227				1,228
	37,743				37,866
Less: accumulated depreciation and amortization	(31,064		)		(29,461		)
	6,679				8,405
Construction in progress	15				41
Property and equipment	6,694				8,446
Less: Impairment of laboratory equipment	(1,841		)	(1)	—
Property and equipment, net	$	4,853			$	8,446

(1)    Plans to utilize certain CodeXol^® assets changed in the second quarter of 2014 such that assets with a a carrying value of $1.8 million were no longer recoverable. Accordingly, the Company recorded an impairment charge of $1.8 million, reducing the carrying value to zero (their estimated fair value, net of costs). The impairment charge was recorded within Research and Development Expense for the three and six months ended June 30, 2014.

Schedule of Finite-Lived Intangible Assets

Intangible assets consisted of the following (in thousands):

	June 30, 2014							December 31, 2013
	Gross Carrying Amount		Accumulated Amortization			Net Carrying Amount		Gross Carrying Amount		Accumulated Amortization			Net Carrying Amount		Weighted- Average Amortization Period
															(years)
Customer relationships	$	3,098	$	(3,098	)	$	—	$	3,098	$	(3,098	)	$	—	5
Developed and core technology	1,534		(1,534		)	—		1,534		(1,534		)	—		5
Maxygen intellectual property	20,244		(12,371		)	7,873		20,244		(10,684		)	9,560		6
Total	$	24,876	$	(17,003	)	$	7,873	$	24,876	$	(15,316	)	$	9,560

Schedule of Finite-Lived Intangible Assets, Future Amortization Expense

The estimated future amortization expense to be charged to research and development through the year ending December 31, 2016 is as follows (in thousands):

Year ending December 31:	Total
2014 (remaining 6 months)	$	1,687
2015	3,374
2016	2,812
	$	7,873