Balance Sheets Details (Tables)

3 Months Ended

Mar. 31, 2014

Balance Sheets Details [Abstract]

Schedule of inventory components

Inventory

Inventory, net consisted of the following (in thousands):

	March 31, 2014		December 31, 2013
Raw materials	$	577	$	763
Work in process	109		31
Finished goods	1,359		693
Inventory, net	$	2,045	$	1,487

Schedule of property and equipment, net

Property and Equipment, net

Property and equipment, net consisted of the following (in thousands):

	March 31, 2014			December 31, 2013
Laboratory equipment	$	23,136		$	23,949
Leasehold improvements	9,493			9,493
Computer equipment	3,209			3,196
Office furniture and equipment	1,228			1,228
	37,066			37,866
Less: accumulated depreciation and amortization	(29,678		)	(29,461		)
	7,388			8,405
Construction in progress	8			41
Property and equipment, net	$	7,396		$	8,446

Schedule of Finite-Lived Intangible Assets

Intangible Assets

Intangible assets consisted of the following (in thousands):

	March 31, 2014							December 31, 2013
	Gross Carrying Amount		Accumulated Amortization			Net Carrying Amount		Gross Carrying Amount		Accumulated Amortization			Net Carrying Amount		Weighted- Average Amortization Period
															(years)
Customer relationships	$	3,098	$	(3,098	)	$	—	$	3,098	$	(3,098	)	$	—	5
Developed and core technology	1,534		(1,534		)	—		1,534		(1,534		)	—		5
Maxygen intellectual property	20,244		(11,528		)	8,716		20,244		(10,684		)	9,560		6
Total	$	24,876	$	(16,160	)	$	8,716	$	24,876	$	(15,316	)	$	9,560

Schedule of Finite-Lived Intangible Assets, Future Amortization Expense

The estimated future amortization expense to be charged to research and development through the year ending December 31, 2016 is as follows (in thousands):

Year ending December 31:	Total
2014 (remaining 9 months)	$	2,530
2015	3,374
2016	2,812
	$	8,716

Schedule of Goodwill

Goodwill

There were no changes in the carrying value of goodwill of $3,241,000 during the first three months of 2014 and 2013.