Selected Quarterly Financial Data (Unaudited)

12 Months Ended

Dec. 31, 2013

Quarterly Financial Information Disclosure [Abstract]

Selected Quarterly Financial Data (Unaudited)

Selected Quarterly Financial Data (Unaudited)

The following table provides the selected quarterly financial data for 2013 and 2012 (in thousands):

Condensed Consolidated Statements of Operations

(In Thousands, Except Per Share Amounts)

	Quarter Ended
	December 31, 2013			September 30, 2013			June 30, 2013			March 31, 2013			December 31, 2012			September 30, 2012			June 30, 2012			March 31, 2012
Revenues:
Product	$	5,263		$	1,076		$	4,948		$	9,136		$	6,834		$	7,140		$	6,783		$	15,167
Collaborative research and development	1,931			2,028			1,609			1,300			1,078			18,569			15,868			14,362
Revenue sharing arrangement	2,331			839			417			1,044			—			—			—			250
Government awards	—			—			—			—			—			632			258			1,357
Total revenues	9,525			3,943			6,974			11,480			7,912			26,341			22,909			31,136
Costs and operating expenses:
Cost of product revenues	4,764			494			3,631			5,665			5,779			6,397			5,829			12,642
Research and development	8,829			6,831			8,624			7,322			10,594			14,191			15,650			16,349
Selling, general and administrative	5,783			5,832			7,169			8,124			7,286			7,909			6,789			9,395
Total costs and operating expenses	19,376			13,157			19,424			21,111			23,659			28,497			28,268			38,386
Loss before income taxes	(9,858		)	(9,227		)	(12,617		)	(9,688		)	(15,711		)	(2,140		)	(5,442		)	(7,293		)
Net loss	$	(9,813	)	$	(9,262	)	$	(12,605	)	$	(9,623	)	$	(15,538	)	$	(2,309	)	$	(5,519	)	$	(7,490	)
Net loss per share, basic and diluted	$	(0.26	)	$	(0.24	)	$	(0.33	)	$	(0.25	)	$	(0.41	)	$	(0.06	)	$	(0.15	)	$	(0.21	)
Weighted average common shares used in computing net loss per share, basic and diluted (1)	38,329			38,102			38,060			37,842			37,581			37,118			36,296			36,057

(1) The full year net loss per share of common stock, basic and diluted, may not equal the sum of the quarters due to weighting of outstanding shares.