Condensed Consolidated Statements of Operations (USD $) In Thousands, except Per Share data, unless otherwise specified	3 Months Ended		9 Months Ended
	Sep. 30, 2013	Sep. 30, 2012	Sep. 30, 2013	Sep. 30, 2012
Revenues:
Product	$ 1,076	$ 7,140	$ 15,161	$ 29,090
Collaborative research and development	2,867	18,569	7,236	49,049
Government awards	0	632	0	2,247
Total revenues	3,943	26,341	22,397	80,386
Costs and operating expenses:
Cost of product revenues	494	6,397	9,790	24,868
Research and development	6,831	14,191	22,776	46,190
Selling, general and administrative	5,832	7,909	21,126	24,093
Total costs and operating expenses	13,157	28,497	53,692	95,151
Loss from operations	(9,214)	(2,156)	(31,295)	(14,765)
Interest income	9	61	53	210
Other expenses	(22)	(45)	(288)	(320)
Loss before (benefit) provision for income taxes	(9,227)	(2,140)	(31,530)	(14,875)
(Benefit) provision for income taxes	35	169	(41)	443
Net loss	$ (9,262)	$ (2,309)	$ (31,489)	$ (15,318)
Net loss per share, basic and diluted (dollars per share)	$ (0.24)	$ (0.06)	$ (0.83)	$ (0.42)
Weighted average common shares used in computing net loss per share, basic and diluted (shares)	38,102	37,116	38,002	36,494