SCHEDULE 13G 0001105806 XXXXXXXX LIVE Common Stock 03/06/2026 0001200375 Codexis, Inc. 192005106 200 Penobscot Drive Redwood City CA 94063 Rule 13d-1(c) LYTTON LAURENCE W X1 4532069.00 0.00 4532069.00 0.00 4532069.00 N 5.0 IN Percentage calculated based on 90,324,383 shares of Common Stock outstanding on November 3, 2025, as reported in the Form 10-Q filed by the Issuer for the quarterly period ended September 30, 2025. Codexis, Inc. 200 Penobscot Drive, Redwood City, CA 94063 Laurence W. Lytton 467 Central Park West New York, NY 10025 USA Y 4,532,069 5.0% 4,532,069 0 4,532,069 0 Y Y Y Y Y N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11. LYTTON LAURENCE W /s/ Laurence W Lytton 03/11/2026