<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0203</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2010-10-18</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001496623</issuerCik>
        <issuerName>NetSpend Holdings, Inc.</issuerName>
        <issuerTradingSymbol>NTSP</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001199270</rptOwnerCik>
            <rptOwnerName>LAMONT ANN H</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O OAK INVESTMENT PARTNERS</rptOwnerStreet1>
            <rptOwnerStreet2>ONE GORHAM ISLAND</rptOwnerStreet2>
            <rptOwnerCity>WESTPORT</rptOwnerCity>
            <rptOwnerState>CT</rptOwnerState>
            <rptOwnerZipCode>06880</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>39597723</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See Note</value>
                    <footnoteId id="F1"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">Represents 38,972,079 shares directly owned by Oak Investment Partners X, LP and 625,644 shares directly owned by Oak X Affiliates Fund, LP.</footnote>
    </footnotes>

    <remarks>Ann H. Lamont is a director of NetSpend Holdings, Inc.  In addition, Ms. Lamont is a managing member of both Oak Associates X, LLC, the general partner of Oak Investment Partners X, LP and Oak X Affiliates, LLC, the general partner of Oak X Affiliates Fund, LP.  Ms. Lamont disclaims beneficial ownership of any securities (except to the extent of her pecuniary interest in such securities), and this report shall not be deemed an admission that such Reporting Person is the beneficial owner of any such securities for purposes of Section 16 or for any other purpose.</remarks>

    <ownerSignature>
        <signatureName>/s/ Ann Huntress Lamont</signatureName>
        <signatureDate>2010-10-18</signatureDate>
    </ownerSignature>
</ownershipDocument>
