X0206 3 2014-01-30 0 0001429560 TREVENA INC TRVN 0001399763 Alta Partners VIII, L.P. C/O ALTA PARTNERS, ONE EMBARCADERO CENTER, 37TH FLOOR SAN FRANCISCO CA 94111 0 0 1 0 0001399894 Alta Partners Management VIII, LLC C/O ALTA PARTNERS, ONE EMBARCADERO CENTER, 37TH FLOOR SAN FRANCISCO CA 94111 0 0 1 0 0001198321 CHAMPSI FARAH C/O ALTA PARTNERS, ONE EMBARCADERO CENTER, 37TH FLOOR SAN FRANCISCO CA 94111 1 0 1 0 0001198330 NOHRA GUY P C/O ALTA PARTNERS, ONE EMBARCADERO CENTER, 37TH FLOOR SAN FRANCISCO CA 94111 0 0 1 0 0001198325 JANNEY DANIEL C/O ALTA PARTNERS, ONE EMBARCADERO CENTER, 37TH FLOOR SAN FRANCISCO CA 94111 0 0 1 0 Common Stock 0 D Series A Preferred Stock Common Stock 967741 I Direct and Indirect -See footnotes Series B Preferred Stock Common Stock 1354838 I Direct and Indirect - See footnotes Series B-1 Preferred Stock Common Stock 314516 I Direct and Indirect - See footnotes Series C Preferred Stock Common Stock 780755 I Direct and Indirect - See footnotes Immediately prior to closing of the issuer's initial public offering, the preferred stock held by the reporting persons will automatically convert into common stock on a 6.2 to 1 basis. The securities are held of record by Alta Partners VIII, L.P. ("APVIII"). Alta Partners Management VIII, LLC ("APMVIII") is the general partner of APVIII. Guy Nohra, Daniel Janney and Farah Champsi are managing directors of APMVIII and exercise shared voting and investment power with respect to the shares onwed by APVIII. Each of the reporting persons disclaims beneficial ownership of such securities, except to the extent of his, her or its proportionate pecuniary interest therein. Ms. Champsi is also a director of the issuer. APVIII holds an aggregate of 6,000,000 shares of Series A Preferred Stock which is convertible into 967,741 shares of Common Stock. APVIII holds an aggregate of 8,400,000 shares of Series B Preferred Stock which is convertible into 1,354,838 shares of Common Stock. APVIII holds an aggregate of 1,950,000 shares of Series B-1 Preferred Stock which is convertible into 314,516 shares of Common Stock. APVIII holds an aggregate of 4,840,686 shares of Series C Preferred Stock which is convertible into 780,755 shares of Common Stock. /s/Derek Colla, Attorney-in-Fact 2014-01-30 Derek Colla, Attorney-in-Fact 2014-01-30 Derek Colla, Attorney-in-Fact 2014-01-30 Derek Colla, Attorney-in-Fact 2014-01-30 Derek Colla, Attorney-in-Fact 2014-01-30