X0202 4 2004-08-20 1 0001034842 RIGEL PHARMACEUTICALS INC RIGL 0001276361 ALTA PARTNERS II INC ONE EMBARCADERO CENTER SUITE 4050 SAN FRANCISCO CA 94111 0 0 0 1 X-ref Alta Partners II 5/20/04 0001163156 ALTA BIOPHARMA PARTNERS II LP ONE EMBARCADERO CENTER SUITE 4050 SAN FRANCISCO CA 94111 0 0 0 1 No longer a 10% Owner 0001163157 ALTA EMBARCADERO BIOPHARMA PARTNERS II LLC ONE EMBARCADERO CENTER SUITE 4050 SAN FRANCISCO CA 94111 0 0 0 1 No longer 10% Owner 0001198321 CHAMPSI FARAH ONE EMBARCADERO CENTER SUITE 4050 SAN FRANCISCO CA 94111 0 0 0 1 See footnotes 0001198328 MARDUEL ALIX ONE EMBARCADERO CENTER SUITE 4050 SAN FRANCISCO CA 94111 0 0 0 1 See footnotes 0001163189 ALTA BIOPHARMA MANAGEMENT II LLC ONE EMBARCADERO CENTER SUITE 4050 SAN FRANCISCO CA 94111 0 0 0 1 No longer 10% Owner Common Stock 2004-08-20 4 D 0 352434 21.111 D 0 I See footnote Common Stock 2004-08-20 4 D 0 8049 21.111 D 0 I See footnote Common Stock 2004-08-20 4 D 0 403892 21.111 D 807784 I See footnote Common Stock 2004-08-20 4 D 0 14858 21.11 D 29715 I See footnote Alta California Partners, L.P. ("ACP") distributed its shares to its general & limited partners on 8/20/04. Jean Deleage, Director, is a General Partner ("GP") of Alta California Mgmt. Partners, L.P. ("ACMP")(which is the GP of ACP) & a managing member of Alta Embarcadero Partners, LLC ("AEP"). Alta Partners ("AP") provides investment advisory services to several venture capital funds including ACP & AEP. The respective GP and members of ACP & AEP exercise sole voting & investment powers with respect to the shares owned by the funds. Jean Deleage,Garrett Gruener & Guy Nohra are general partners of ACMP, and Jean eleage & Garrett Gruener are members of AEP (collectively known as the "principals"). As GP & members, they may be deemed to share voting & investment powers over the shares owned by the foregoing funds. The principals disclaim beneficial ownership of all such shares held by the foregoing funds, except to the extent of their proportionate pecuniary interests therein. Alta Embarcadero Partners, LLC distributed it shares of Common Stock to its members on 8/20/04. See footnote for Alta California Partners, L.P. on this Form 4. Alta BioPharma Partners II, L.P. ("ABPII") distributed 403,892 shares to its general and limited partners on 8/20/04. Jean Deleage, Director, is a managing director of Alta BioPharma Mgmt.II, LLC (which is the General Partner ("GP") of ABPII) & a manager of Alta Embarcadero BioPharma Partners II, LLC ("AEBPII"). Alta Partners II, Inc. ("APII") provides investment advisory services to several venture capital funds including ABPII & AEBPII. The respective GP and managers exercise sole voting & investment powers over the shares held by the foregoing funds. Jean Deleage, Alix Marduel & Farah Champsi (collectively known as the "principals") are managing directors ("md") of ABPII & managers of AEBPII. As md & managers, they may be deemed to share voting & investment powers over the shares held by the funds. The principals disclaim beneficial ownership of all such share held by the foregoing funds, except to the extent of their proportionate pecuniary interests therein. Alta Embarcadero BioPharma Partners II, LLC distributed 14,858 shares to its members. See footnote for Alta BioPharma Partners II, L.P. on this Form 4. Cross reference with the Form 4 filed on 08/20/2004 for Jean Deleage. Jean Deleage 2004-08-24 Farah Champsi 2004-08-23 Farah Champsi 2004-08-23 Farah Champsi 2004-08-23 Farah Champsi 2004-08-23 Farah Champsi 2004-08-24