X0303 4 2010-03-22 0000927653 MCKESSON CORP MCK 0001197897 OWEN MARC E ONE POST STREET SAN FRANCISCO CA 94104 0 1 0 0 EVP, Corp.Strategy & Bus. Dev. Common Stock 2010-03-22 4 M 0 10000 34.94 A 14033.3995 D Common Stock 2010-03-22 4 M 0 45000 39.81 A 59033.3995 D Common Stock 2010-03-22 4 M 0 10000 34.36 A 69033.3995 D Common Stock 2010-03-22 4 S 0 65000 65.00 D 4033.3995 D Common Stock 1398.0697 I By Profit-Sharing Investment Plan Employee Stock Option (Right-to-buy) 34.94 2010-03-22 4 M 0 10000 0 D 2005-03-31 2011-05-25 Common Stock 10000 0 D Employee Stock Option (Right-to-buy) 39.81 2010-03-22 4 M 0 45000 0 D 2011-10-25 Common Stock 45000 30000 D Employee Stock Option (Right-to-buy) 34.36 2010-03-22 4 M 0 10000 0 D 2004-01-27 2013-07-30 Common Stock 10000 0 D Includes 4,033.3995 shares purchased under the Issuer's ESPP. Option exercise and sale pursuant to a previously adopted plan dated 03/13/2009, intended to comply with Rule 10b5-1(c). This option was granted on 10/26/2001 and vested in 3 installments as follows: 50% vested on the 2nd anniversary of the grant date and 25% vested on each of the 3rd and 4th anniversary of the grant date. Donna Spinola, Attorney-in-fact 2010-03-23