X0101 42003-07-02 0000875320 VERTEX PHARMACEUTICALS INC / MA VRTX 0001197020 SATO VICKI L 0100PresidentCommon Stock2003-07-024M038007.88A107454DCommon Stock2003-07-024S0380014.58D103654DStock Option7.882003-07-024M038000D1994-03-312003-11-30Common Stock38001258900DTransaction made pursuant to Dr. Sato's company approved trading plan established under Rule 10b5-1.Includes 7,046 (I) shares 401(k).Right to buy under 1991 Stock and Option Plan, vesting in 20 equal quarterly installments from 12/01/1993.Kenneth S. Boger, Attorney-In-Fact2003-07-03