X0201 42003-12-11 0000875320 VERTEX PHARMACEUTICALS INC / MA VRTX 0001197014 ALAM JOHN J C/O VERTEX PHARMACEUTICALS INCORPORATED 130 WAVERLY STREET CAMBRIDGE MA 01239 0100SVP, Drug Eval. & Appr.Common Stock2003-12-114A019200A19454DCommon Stock2612I401(k)Stock Option9.072003-12-114A0144000A2004-03-112013-12-10Common Stock14400332645DStock grant made under 1996 Stock and Option Plan, vesting in 4 equal annual installments from 12/11/2003.Right to buy under 1996 Stock and Option Plan, vesting in 16 equal quarterly installments from 12/11/2003.Valerie L. Andrews, Attorney-In-Fact2003-12-15