X0303 4 2010-04-27 0001267602 ALIMERA SCIENCES INC ALIM 0001196863 VITULLO NICOLE C/O DOMAIN ASSOCIATES, LLC ONE PALMER SQUARE PRINCETON NJ 08542 0 0 1 0 Common Stock 2010-04-27 4 C 0 4451745 A 4451745 I By Domain Partners VI, L.P. Common Stock 2010-04-27 4 C 0 47704 A 47704 I By DP VI Associates, L.P. Common Stock 2010-04-27 4 P 0 378028 11.00 A 4829773 I By Domain Partners VI, L.P. Series A Preferred Stock 2010-04-27 4 C 0 1631866 D Common Stock 1631866 0 I By Domain Partners VI, L.P. Series B Preferred Stock 2010-04-27 4 C 0 1109970 D Common Stock 1109970 0 I By Domain Partners VI, L.P. Series C Preferred Stock 2010-04-27 4 C 0 1141486 D Common Stock 1141486 0 I By Domain Partners VI, L.P. Series C-1 Preferred Stock 2010-04-27 4 C 0 568423 D Common Stock 568423 0 I By Domain Partners VI, L.P. Series A Preferred Stock 2010-04-27 4 C 0 17486 D Common Stock 17486 0 I By DP VI Associates, L.P. Series B Preferred Stock 2010-04-27 4 C 0 11894 D Common Stock 11894 0 I By DP VI Associates, L.P. Series C Preferred Stock 2010-04-27 4 C 0 12233 D Common Stock 12233 0 I By DP VI Associates, L.P. Series C-1 Preferred Stock 2010-04-27 4 C 0 6091 D Common Stock 6091 0 I By DP VI Associates, L.P. All outstanding shares of the Issuer's preferred stock were automatically converted into Common Stock upon the closing of the Issuer's initial public offering, for no additional consideration. The Reporting Person is a managing member of One Palmer Square Associates VI, L.L.C., which is the sole general partner of Domain Partners VI, L.P. and DP VI Associates, L.P. Pursuant to Instruction 4(b)(iv) of Form 4, the Reporting Person has elected to report as indirectly beneficially owned the entire number of securities beneficially owned by each such entity. The Reporting Person disclaims beneficial ownership of any securities, and any proceeds thereof, that exceed his or her pecuniary interest therein and/or that are not actually distributed to him or her. /s/Kathleen K. Schoemaker, Attorney-in-Fact 2010-04-27