X0306 4 2022-03-02 0 0001000228 HENRY SCHEIN INC HSIC 0001194347 BRESLAWSKI JAMES P C/O HENRY SCHEIN, INC. 135 DURYEA ROAD MELVILLE NY 11747 1 1 0 0 Vice Chairman, President Common Stock, par value $0.01 per share 2022-03-02 4 F 0 3331 85.75 D 229904 D Common Stock, par value $0.01 per share 2022-03-03 4 S 0 5893 85.92 D 224011 D Common Stock, par value $0.01 per share 2022-03-03 4 F 0 2054 87.24 D 221957 D Represents the surrender of shares to the Issuer to satisfy the reporting person's tax withholding obligation upon the vesting of the reporting person's March 2, 2018 grant of time-based restricted stock/units. The sale transaction reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan of the reporting person dated December 14, 2021. Represents the surrender of shares to the Issuer to satisfy the reporting person's tax withholding obligation upon the vesting of the reporting person's March 3, 2021 grant of time-based restricted stock/units. /s/ Jennifer Ferrero (as Attorney-in-Fact for James P. Breslawski) 2022-03-04