SEC Form 4

FORM 4		UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940	OMB APPROVAL OMB Number: 3235-0287 Estimated average burden hours per response: 0.5
	Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

1. Name and Address of Reporting Person* ADAMS STREET PARTNERS LLC (Last) (First) (Middle) ONE NORTH WACKER DRIVE SUITE 2700 (Street) CHICAGO IL 60606 (City) (State) (Zip)	2. Issuer Name and Ticker or Trading Symbol Aptinyx Inc. [ APTX ]	5. Relationship of Reporting Person(s) to Issuer (Check all applicable) Director X 10% Owner Officer (give title below) Other (specify below)
	3. Date of Earliest Transaction (Month/Day/Year) 01/10/2020
	4. If Amendment, Date of Original Filed (Month/Day/Year)	6. Individual or Joint/Group Filing (Check Applicable Line) X Form filed by One Reporting Person Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	01/10/2020		P		152,512(8)	A	$3	691,176	I	See footnote(1)(7)
Common Stock	01/10/2020		P		115,367(8)	A	$3	522,837	I	See footnote(2)(7)
Common Stock	01/10/2020		P		156,920(8)	A	$3	711,151	I	See footnote(3)(7)
Common Stock	01/10/2020		P		120,453(8)	A	$3	504,708	I	See footnote(4)(7)
Common Stock	01/10/2020		P		104,942(8)	A	$3	439,714	I	See footnote(5)(7)
Common Stock	01/10/2020		P		349,806(8)	A	$3	1,465,716	I	See footnote(6)(7)
Common Stock								695,326	I	See footnote(9)(7)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. The shares are held directly by Adams Street 2012 Direct Fund LP ("AS 2012").

2. The shares are held directly by Adams Street 2013 Direct Fund LP ("AS 2013").

3. The shares are held directly by Adams Street 2014 Direct Fund LP ("AS 2014").

4. The shares are held directly by Adams Street 2015 Direct Venture/Growth Fund LP ("AS 2015").

5. The shares are held directly by Adams Street 2016 Direct Venture/Growth Fund LP ("AS 2016").

6. The shares are held directly by Adams Street Venture/Growth Fund VI LP ("ASVG VI").

7. Adams Street Partners, LLC is the managing member of the general partner of each of AS 2008, AS 2009, and AS 2010, and the managing member of the general partner of the general partner of AS 2011 (along with AS 2008, AS 2009 and AS 2010, as defined in footnote 9), AS 2012, AS 2013, AS 2014, AS 2015, AS 2016 and ASVG VI. Thomas S. Bremner, Jeffrey T. Diehl, Elisha P. Gould III, Robin P. Murray and Fred Wang, each of whom is a partner of Adams Street Partners, LLC (or a subsidiary thereof), may be deemed to have shared voting and investment power over the reported shares. Adams Street Partners, LLC and Thomas S. Bremner, Jeffrey T. Diehl, Elisha P. Gould III, Robin P. Murray and Fred Wang disclaim beneficial ownership of the shares held by each of the aforementioned funds except to the extent of their pecuniary interest therein.

8. On January 10, 2020, AS 2012, AS 2013, AS 2014, AS 2015, AS 2016, and ASVG VI purchased 152,512, 115,367, 156,920, 120,453, 104,942, and 349,806 shares of common stock of the Issuer at a price of $3.00 per share, respectively, pursuant to an underwritten public offering.

9. Represents 249,791 shares of Common Stock held by Adams Street 2008 Direct Fund, L.P. ("AS 2008"), 216,053 shares of Common Stock held by Adams Street 2009 Direct Fund, L.P. ("AS 2009"), 122,728 shares of Common Stock held by Adams Street 2010 Direct Fund, L.P. ("AS 2010"), and 106,754 shares of Common Stock held by Adams Street 2011 Direct Fund LP ("AS 2011").

	/s/ Sara Robinson Dasse	01/14/2020
	** Signature of Reporting Person	Date
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