X0306 4 2016-05-03 0000820081 CAMBREX CORP CBM 0001192621 KLOSK STEVEN M ONE MEADOWLANDS PLAZA EAST RUTHERFORD NJ 07073 1 1 0 0 President & CEO Common Stock 2016-05-03 4 M 0 3500 4.38 A 136828 D Common Stock 2016-05-03 4 S 0 3500 49.51 D 133328 D Common Stock 2016-05-05 4 M 0 12930 4.38 A 146258 D Common Stock 2016-05-05 4 S 0 12930 49.03 D 133328 D Stock Option (right to buy) 4.38 2016-05-03 4 M 0 3500 0 A 2017-04-21 Common Stock 3500 26935 D Stock Option (right to buy) 4.38 2016-05-05 4 M 0 12930 0 A 2017-04-21 Common Stock 12930 14005 D The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $49.50 to $49.53 inclusive. The reporting person undertakes to provide to Cambrex Corporation, any security holder of Cambrex Corporation, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in Footnote 1 to the Form 4. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $49.00 to $49.25 inclusive. The reporting person undertakes to provide to Cambrex Corporation, any security holder of Cambrex Corporation, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in Footnote 2 to the Form 4. The option representing a right to purchase 150,000 shares became exercisable in four equal installments beginning April 21, 2011 which was the first anniversary of the date on which the option was granted. Danielle Mann for Steven M. Klosk by POA 2016-05-05