X0202 4 2006-05-01 0001002637 MILLENNIUM PHARMACEUTICALS INC MLNM 0001192613 SELBY NORMAN C PERSEUS, L.L.C. 1325 AVENUE OF THE AMERICAS NEW YORK, NY 10019 1 0 0 0 Common stock 7000 D Common stock 1143 I by spouse Common stock 1010 I by trust for son Common stock 1010 I by trust for son Stock option (right to buy) 8.99 2006-05-01 4 A 0 5000 0 A 2016-05-01 Common stock 5000 5000 D Held by Mr. Selby's spouse. Mr. Selby disclaims beneficial ownership of these shares. Held by a Trust for Mr. Selby's son. Mr. Selby disclaims beneficial ownership of these shares. Held by a Trust for Mr. Selby's son. Mr. Selby disclaims beneficial ownership of these shares. This is the first of three consecutive monthly stock option grants which in the aggregate are the reporting person's annual non-employee director grant of 15,000 shares. Becomes exercisable for 1/12th of the number of shares granted beginning 06/01/2006. Joel S. Goldberg, Attorney-In-Fact 2006-05-03