CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021
Operating Activities
Net loss	$ (67,735)	$ (27,721)
Adjustments to reconcile net loss to net cash (used in) provided by operating activities:
Depreciation	4,710	3,475
Amortization of intangible assets	18,684	18,684
Amortization of lease right-of-use assets	3,378	3,519
Amortization of debt issuance costs	1,030	1,030
Deferred income tax benefit	(17)	(72)
Gain on disposal of fixed assets	29	(3)
Stock-based compensation	26,873	22,921
Unrealized foreign currency losses	4,219	1,836
Amortization of premium on short-term investments	601	773
Other liabilities		1,951
Changes in operating assets and liabilities:
Accounts receivable, net	(3,121)	494
Inventory	(11,881)	(4,257)
Prepaid expenses and other current assets	(3,355)	(5,039)
Accounts payable and accrued liabilities	(1,847)	11,666
Other assets	(515)	102
Net cash (used in) provided by operating activities	(28,947)	29,359
Investing activities
Purchases of short-term investments	(47,256)	(191,756)
Proceeds from sales and maturities of short-term investments	97,494	182,356
Purchases of property and equipment	(22,044)	(38,458)
Proceeds from disposal of property and equipment	96	3
Investment in company-owned life insurance	(166)	(1,505)
Net cash provided by (used in) investing activities	28,124	(49,360)
Financing activities
Proceeds from exercise of stock options	2,871	24,383
Proceeds from share purchases under Employee Stock Purchase Plan	5,630	4,817
Payment of employee taxes related to vested restricted stock units	(2,399)	(3,670)
Principal paid on finance lease	(380)	(555)
Proceeds from tenant improvement allowance		12,668
Net cash provided by financing activities	5,722	37,643
Effect of exchange rate changes on cash and cash equivalents	(1,927)	(1,257)
Net increase in cash, cash equivalents and restricted cash	2,972	16,385
Cash, cash equivalents and restricted cash at beginning of period	110,124	106,162
Cash, cash equivalents and restricted cash at end of period	113,096	122,547
Supplemental disclosures of cash flow information
Taxes paid	372	307
Interest paid on convertible senior notes	3,953	3,953
Other interest paid	3,350	2,983
Supplemental schedule of noncash investing and financing activities
Purchases of property and equipment included in accounts payable and accrued liabilities	$ 3,258	$ 2,244