X0202 4/A 2005-12-02 2005-11-28 0000875320 VERTEX PHARMACEUTICALS INC / MA VRTX 0001190290 ULLIAN ELAINE C/O VERTEX PHARMACEUTICALS INCORPORATED 130 WAVERLY STREET CAMBRIDGE MA 02139 1 0 0 0 Common Stock 2005-12-02 4 S 0 600 25.03 D 0 D This Form 4 amends the Form 4 filed on behalf of Ms. Ullian on November 28, 2005 to reflect a different transaction date and price. Valerie L. Andrews, Attorney-In-Fact 2005-12-05