X0306 4 2015-12-29 0 0001108205 CURIS INC CRIS 0001190121 PASSERI DANIEL R 4 MAGUIRE ROAD LEXINGTON MA 02421 1 0 0 0 Common stock 2015-12-29 4 M 0 11200 1.57 A 210098 D Common stock 2015-12-29 4 S 0 11200 2.91 D 198898 D Common stock 2015-12-30 4 M 0 14400 1.57 A 213298 D Common stock 2015-12-30 4 S 0 14400 3.01 D 198898 D Employee stock option 1.57 2015-12-29 4 M 0 11200 1.57 D 2010-05-31 2016-05-31 Common stock 11200 0 D Employee stock option 1.57 2015-12-30 4 M 0 14400 1.57 D 2010-05-31 2016-05-31 Common stock 14400 0 D These shares were sold between $2.81-$2.99/share pursuant to an effective 10b5-1 plan. The Company will provide, upon request, full information regarding the number of shares sold at each separate price. These shares were sold between $2.93-$3.10/share pursuant to an effective 10b5-1 plan. The Company will provide, upon request, full information regarding the number of shares sold at each separate price. Options vested over a four-year period and became fully vested on May 31, 2010. /s/ Michael P. Gray, attorney-in-fact 2015-12-30