X0306 4 2016-09-14 0 0001626878 XBiotech Inc. XBIT 0001189152 VASELLA DANIEL 8201 EAST RIVERSIDE DRIVE BUILDING 4, SUITE 100 AUSTIN TX 78744 1 0 0 0 Stock Option 13.26 2016-09-14 4 M 0 50000 13.26 A 2016-09-14 2026-09-13 Common Stock 50000 50000 D On September 14, 2016 (the Grant Date) Daniel Vasella was granted nonstatutory stock options (the Options) under the Company's 2015 Equity Incentive Plan to purcahse shares of the Company's Common Stock (the Shares) at an exercise price equal to the closing sales price of the Shares on the Grant Date as quoted by the Nasdaq Stock Market, with an expiry of ten years from the Grant Date. Half of the Options vest on December 20, 2016 and another half of the Options vest on June 20, 2017. /s/ Daniel Vasella 2016-09-16