X0206 3 2021-02-11 0 0001656536 Decibel Therapeutics, Inc. DBTX 0001189014 POON CHRISTINE A C/O DECIBEL THERAPEUTICS, INC. 1325 BOYLSTON STREET, SUITE 500 BOSTON MA 02215 1 0 0 0 Stock Option (right to buy) 25.97 2029-06-18 Common Stock 4716 D The option was granted on June 19, 2019 for 4,716 shares. The shares underlying the option are scheduled to vest over four years in equal quarterly installments through June 19, 2023. Exhibit Index: 24.1 Power of Attorney /s/ Ronald Vigliotta, Attorney-in-Fact 2021-02-11