X0508 4 2023-08-03 0 0001888886 Structure Therapeutics Inc. GPCR 0001188919 LOVE TED W C/O STRUCTURE THERAPEUTICS INC. 611 GATEWAY BLVD., SUITE 223 SOUTH SAN FRANCISCO CA 94080 1 0 0 0 0 Stock option (right to buy) 10.57 2023-08-03 4 A 0 75000 0.00 A 2033-08-02 Ordinary Shares 75000 75000 D The option exercise price per share is equal to the fair market value per Ordinary Share on the grant date based on the trading price of the Issuer's American Depositary Shares ("ADSs"). The shares vest in equal monthly installments over a three-year period such that the option is fully vested on the third anniversary of August 3, 2023. The Ordinary Shares of the Issuer may be represented by ADSs. Each ADS represents three Ordinary Shares of the Issuer. /s/ Jun Yoon, Attorney-in-Fact 2023-08-04