X0306 4 2020-10-01 0 0000872589 REGENERON PHARMACEUTICALS, INC. REGN 0001187443 RYAN ARTHUR F 777 OLD SAW MILL RIVER ROAD TARRYTOWN NY 10591 1 0 0 0 Common Stock 2020-10-01 4 S 0 2 553.73 D 28441 D Common Stock 2020-10-01 4 S 0 8 554.61 D 28433 D Common Stock 2020-10-01 4 S 0 30 555.52 D 28403 D Common Stock 2020-10-01 4 S 0 10 556.5 D 28393 D Common Stock 2020-10-01 4 S 0 2 557.44 D 28391 D Common Stock 2020-10-01 4 S 0 11 558.63 D 28380 D Common Stock 2020-10-01 4 S 0 12 559.43 D 28368 D Common Stock 2020-10-01 4 S 0 6 560.41 D 28362 D Common Stock 2020-10-01 4 S 0 4 561.48 D 28358 D Common Stock 2020-10-01 4 S 0 5 562.63 D 28353 D Common Stock 2020-10-01 4 S 0 1 563.8 D 28352 D Common Stock 2020-10-01 4 S 0 7 564.25 D 28345 D Common Stock 2020-10-01 4 S 0 2 565.22 D 28343 D Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c). Represents volume-weighted average price of sales of 2 shares of Company stock on October 1, 2020 at prices ranging from $553.46 to $553.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 1, 2020 at each separate price. Represents volume-weighted average price of sales of 8 shares of Company stock on October 1, 2020 at prices ranging from $554.20 to $554.90. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 1, 2020 at each separate price. Represents volume-weighted average price of sales of 30 shares of Company stock on October 1, 2020 at prices ranging from $555.00 to $555.98. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 1, 2020 at each separate price. Represents volume-weighted average price of sales of 10 shares of Company stock on October 1, 2020 at prices ranging from $556.00 to $556.91. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 1, 2020 at each separate price. Represents volume-weighted average price of sales of 2 shares of Company stock on October 1, 2020 at prices ranging from $557.22 to $557.65. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 1, 2020 at each separate price. Represents volume-weighted average price of sales of 11 shares of Company stock on October 1, 2020 at prices ranging from $558.28 to $558.92. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 1, 2020 at each separate price. Represents volume-weighted average price of sales of 12 shares of Company stock on October 1, 2020 at prices ranging from $559.01 to $559.68. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 1, 2020 at each separate price. Represents volume-weighted average price of sales of 6 shares of Company stock on October 1, 2020 at prices ranging from $560.00 to $560.92. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 1, 2020 at each separate price. Represents volume-weighted average price of sales of 4 shares of Company stock on October 1, 2020 at prices ranging from $561.09 to $561.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 1, 2020 at each separate price. Represents volume-weighted average price of sales of 5 shares of Company stock on October 1, 2020 at prices ranging from $562.45 to $562.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 1, 2020 at each separate price. Represents volume-weighted average price of sales of 7 shares of Company stock on October 1, 2020 at prices ranging from $564.00 to $564.79. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 1, 2020 at each separate price. Represents volume-weighted average price of sales of 2 shares of Company stock on October 1, 2020 at prices ranging from $565.13 to $565.30. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 1, 2020 at each separate price. /s/**Arthur F. Ryan 2020-10-05