X0306 4 2022-06-09 0 0001367920 CONCERT PHARMACEUTICALS, INC. CNCE 0001185039 ALDRICH RICHARD C/O CONCERT PHARMACEUTICALS, INC. 65 HAYDEN AVENUE, SUITE 3000N LEXINGTON MA 02421 1 0 0 0 Common Stock 2022-06-09 4 A 0 16400 A 358500 D Common Stock 210526 I By Richard H. Aldrich 2018 Revocable Trust Common Stock 44351 I By Little Eagles, LLC Stock Option (right to buy) 5.00 2022-06-09 4 A 0 22410 0.00 A 2032-06-08 Common Stock 22410 22410 D Represents a grant of restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of Common Stock of the Issuer. These RSUs vest in full on the earlier of (i) June 9, 2023 and (ii) the date that is one business day prior to the date of the Issuer's next annual meeting of stockholders. The amount listed represents the maximum number of shares of Common Stock of the Issuer that may be delivered pursuant to the grant. Not applicable. Shares held by the Richard H. Aldrich 2018 Revocable Trust. Mr. Aldrich is the sole trustee of the Richard H. Aldrich 2018 Revocable Trust. Mr. Aldrich disclaims beneficial ownership of such shares except to the extent of any pecuniary interest therein. Shares held by Little Eagles, LLC. The owners of Little Eagles, LLC are the Richard H. Aldrich Irrevocable Trust of 2011 and trusts established for the benefit of Mr. Aldrich's minor children. The trustees of the Richard H. Aldrich Irrevocable Trust of 2011 are Mr. Aldrich's spouse, Nichole A. Aldrich, and Mr. Aldrich's brother, Caleb F. Aldrich. The beneficiaries of the Richard H. Aldrich Irrevocable Trust of 2011 are Mr. Aldrich's minor children. Mr. Aldrich disclaims beneficial ownership of such shares except to the extent of any pecuniary interest therein. This option was granted based on Mr. Aldrich's election to receive his annual cash compensation in the form of a stock option. The shares underlying this option vest in equal quarterly installments over a one-year period through June 9, 2023, provided that such option shall vest in full on the date that is one business day prior to the date of the Issuer's next annual meeting of stockholders (if earlier than June 9, 2023). /s/ Jeffrey A. Munsie, attorney-in-fact 2022-06-13