X0306 4 2014-10-16 0 0001367920 CONCERT PHARMACEUTICALS, INC. CNCE 0001185039 ALDRICH RICHARD C/O CONCERT PHARMACEUTICALS, INC. 99 HAYDEN AVENUE, SUITE 500 LEXINGTON MA 02421 1 0 0 0 Common Stock 2014-10-16 5 G 0 E 20012 0.00 D 82405 I By Richard H. Aldrich 2011 GRAT Common Stock 2014-10-16 5 G 0 E 20012 0.00 A 306975 D Common Stock 2014-10-16 5 G 0 E 82405 0.00 D 0 I By Richard H. Aldrich 2011 GRAT Common Stock 2014-10-16 5 G 0 E 82405 0.00 A 82405 I By Richard H. Aldrich Irrevocable Trust of 2011 Common Stock 61946 I By Little Bear Associates, Inc. Shares held by Richard H. Aldrich 2011 GRAT. Mr. Aldrich is the sole trustee of the Richard H. Aldrich 2011 GRAT. Mr. Aldrich disclaims beneficial ownership of such shares except to the extent of any pecuniary interest therein. Shares held by Richard H. Aldrich Irrevocable Trust of 2011. The trustees of Richard H. Aldrich Irrevocable Trust of 2011 are Mr. Aldrich's spouse, Nichole A. Aldrich, and Mr. Aldrich's brother, Caleb F. Aldrich. The beneficiaries of Richard H. Aldrich Irrevocable Trust of 2011 are Mr. Aldrich's minor children. Mr. Aldrich disclaims beneficial ownership of such shares except to the extent of any pecuniary interest therein. Shares held by Little Bear Associates, Inc., formerly known as RA Capital Associates, Inc. Mr. Aldrich is the sole stockholder of Little Bear Associates, Inc. /s/ Ryan Daws (as attorney-in-fact for Richard H. Aldrich) 2014-10-21