X0306 4 2015-06-08 1 0001070081 PTC THERAPEUTICS, INC. PTCT 0001185039 ALDRICH RICHARD C/O PTC THERAPEUTICS, INC. 100 CORPORATE COURT SOUTH PLAINFIELD NJ 07080 1 0 0 0 Common Stock 2015-06-08 4 M 0 7000 10.85 A 7000 D Common Stock 2015-06-08 4 S 0 6896 55.65 D 104 D Common Stock 2015-06-08 4 S 0 104 56.05 D 0 D Stock Option (Right to Buy) 10.85 2015-06-08 4 M 0 7000 0 D 2025-06-09 Common Stock 7000 13000 D Stock Option (Right to Buy) 27.05 2015-01-28 2024-01-27 Common Stock 10000 10000 D Stock Option (Right to Buy) 51.00 2016-01-02 2025-01-01 Common Stock 12000 12000 D The transactions reported in this Form 4 were effected pursuant to a written Rule 10b5-1 plan adopted by the reporting person. This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $55.05 to $56.04 per share. The reporting person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $56.05 to $56.08 per share. The reporting person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. This option was granted on May 15, 2013 and vests over three years, with 8.33% of the shares underlying the option vested on August 15, 2013 and an additional 8.33% of the original number of shares underlying the option vesting at the end of each successive three-month period thereafter. /s/ Colleen Diver Johnson, attorney-in-fact 2015-06-10