X0306 4 2013-09-11 0 0001544227 OvaScience, Inc. OVAS 0001185039 ALDRICH RICHARD C/O OVASCIENCE, INC., 215 FIRST STREET, SUITE 240 CAMBRIDGE MA 02142 1 0 1 0 Common Stock 2013-09-11 4 P 0 4850 10.54 A 4850 I by Richard H. Aldrich 2005 Revocable Trust Common Stock 526445 D Common Stock 175481 I by Richard H. Aldrich Revocable Trust of 2011 Common Stock 3720571 I By Longwood Fund, LP The trustee of the Richard H. Aldrich 2005 Revocable Trust is the reporting person and he exercises sole voting and investment power over the shares of record held by the trust. The trustee of the Richard H. Aldrich Irrevocable Trust of 2011 is the reporting person's spouse, Nichole Aldrich, and she exercises sole voting and investment power over the shares of record held by the trust. Longwood Fund GP, LLC is the general partner of Longwood Fund, LP. Voting and investment power with respect to the shares held by Longwood Fund, LP are vested in Richard Aldrich, Michelle Dipp, M.D., Ph.D. and Christoph Westphal, M.D., Ph.D. (collectively, the "Managers"), the managers of Longwood Fund GP, LLC. Each of the Managers disclaims beneficial ownership of the shares held by Longwood Fund, LP, except to the extent of their respective pecuniary interest therein, and the inclusion of these shares in the report shall not be deemed an admission of beneficial ownership of the shares for purposes of Section 16 or for any other purpose. /s/ Christopher Bleck, Attorney-in-fact 2013-09-11