X0303 4 2010-06-30 0000901219 HUMAN GENOME SCIENCES INC HGSI 0001184419 DREWS JURGEN 14200 SHADY GROVE ROAD ROCKVILLE MD 20850 1 Common Stock 2010-06-30 4 M 0 20732 10.69 A 30773 D Common Stock 2010-06-30 4 M 0 11120 5.97 A 41893 D Common Stock 2010-06-30 4 M 0 5782 2.09 A 47675 D Common Stock 2010-06-30 4 S 0 300 23.5467 D 47375 D Common Stock 2010-06-30 4 S 0 5782 23.3435 D 41593 D Common Stock 2010-06-30 4 S 0 11120 23.3887 D 30473 D Common Stock 2010-06-30 4 S 0 20432 23.1814 D 10041 D Non-Employee Director Stock Option - Right to Buy 10.69 2010-06-30 4 M 0 20732 0 D 2014-05-21 Common Stock 20732 0 D Non-Employee Director Stock Option - Right to Buy 5.97 2010-06-30 4 M 0 11120 0 D 2018-05-08 Common Stock 11120 4880 D Non-Employee Director Stock Option - Right to Buy 2.09 2010-06-30 4 M 0 5782 0 D 2019-05-07 Common Stock 5782 10218 D This transaction was executed in multiple trades at 23.55. The price reported above reflects the weighted average sale price. Upon written request by the Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price is available. This transaction was executed in multiple trades at prices ranging from $22.91 to $23.63. The price reported above reflects the weighted average sale price. Upon written request by the Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price is available. This transaction was executed in multiple trades at prices ranging from $22.91 to $23.69. The price reported above reflects the weighted average sale price. Upon written request by the Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price is available. This transaction was executed in multiple trades at prices ranging from $22.53 to $23.51. The price reported above reflects the weighted average sale price. Upon written request by the Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price is available. These options have vested and are fully exercisable. James H. Davis, Pursuant to Power of Attorney 2010-07-01