Research and Development Agreements - Schedule of Research and Development Revenues Disaggregated by Location (Detail) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Revenue Recognition [Line Items]
Total research and development revenue	$ 8,486	$ 3,220
JAPAN
Revenue Recognition [Line Items]
Total research and development revenue	2,586	237
UNITED STATES
Revenue Recognition [Line Items]
Total research and development revenue	$ 5,900	$ 2,983