X0303 4 2010-03-01 0 0000933974 BROOKS AUTOMATION INC BRKS 0001182721 LEPOFSKY ROBERT C/O BROOKS AUTOMATION, INC. 15 ELIZABETH DRIVE CHELMSFORD MA 01824 1 1 0 0 Chief Executive Officer Common Stock 2010-03-01 4 F 0 25400 8.64 D 894695 D Common Stock 2170 I By managed account Forfeiture of shares by the reporting person to satisfy the reporting person's obligations with respect to withholding taxes in connection with the vesting on March 1, 2010 of 80,000 shares of restricted stock held by the reporting person. These shares are held by the reporting person's 401K Plan. /s/ Thomas S. Grilk, attorney-in-fact for Robert J. Lepofsky 2010-03-03