X0303 4 2008-08-07 0001099800 EDWARDS LIFESCIENCES CORP EW 0001182467 LYLE CORINNE H ONE EDWARDS WAY IRVINE CA 92614 1 CVP & Pres., Global Ops Common Stock 2008-08-07 4 M 0 10000 30.43 A 36857 D Common Stock 2008-08-07 4 S 0 2700 55.5189 D 34157 D Common Stock 2008-08-07 4 S 0 7300 54.9582 D 26857 D Common Stock 2252 I 401(k) Employee Stock Option (Right to Acquire) 30.43 2008-08-07 4 M 0 10000 30.43 D 2004-05-14 2010-05-13 Common Stock 10000 20000 D This Form 4 reflects changes in beneficial ownership only; it does not identify other securities of the Issuer beneficially owned by the reporting person. This amount includes quarterly acquisition of shares under the Edwards Lifesciences Corporation Employee Stock Purchase Plan as reflected on the most recent report of the plan administrator. This transaction was executed in multiple trades at prices ranging from $55.25 to $56.1587. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $54.235 to $55.23. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. Shares represented on the most recent statement of the 401(k) Plan Administrator where a unitized accounting procedure is utilized to convert the equities to share equivalents. This Form 4 reflects changes in beneficial ownership only; it does not identify other securities of the Issuer beneficially owned by the reporting person. /s/ Jay P. Wertheim, Attorney-in-Fact 2008-08-08