144 0001180770 XXXXXXXX LIVE 0000939767 EXELIXIS, INC. 000-30235 1851 HARBOR BAY PARKWAY ALAMEDA CA 94502 6508377000 POSTE GEORGE Director COMMON MORGAN STANLEY SMITH BARNEY LLC EXECUTIVE SERVICES

200 W CIVIC CENTER DR - 4TH FLOOR SANDY UT 84070

30000 1020111.66 285600000 11/01/2024 NASDAQ COMMON 01/01/2016 RESTRICTED STOCK ISSUER N 12745 01/01/2016 COMPENSATION COMMON 07/03/2015 RESTRICTED STOCK ISSUER N 4510 07/03/2015 COMPENSATION COMMON 10/02/2015 RESTRICTED STOCK ISSUER N 12745 10/02/2015 COMPENSATION N GEORGE POSTE

1851 HARBOR BAY PARKWAY ALAMEDA CA 94502

RESTRICTED STOCK 08/08/2024 33725 906746.10 11/01/2024 /s/ George Poste