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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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<SEC-DOCUMENT>0001144204-07-011333.txt : 20070306
<SEC-HEADER>0001144204-07-011333.hdr.sgml : 20070306
<ACCEPTANCE-DATETIME>20070306142419
ACCESSION NUMBER:		0001144204-07-011333
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20070302
FILED AS OF DATE:		20070306
DATE AS OF CHANGE:		20070306

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			SURGENOR TIMOTHY R
		CENTRAL INDEX KEY:			0001304823

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-50505
		FILM NUMBER:		07674303

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		508-549-9981

	MAIL ADDRESS:	
		STREET 1:		100 FOXBOROUGH BOULEVARD
		STREET 2:		SUITE 240
		CITY:			FOXBOROUGH
		STATE:			MA
		ZIP:			02035

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Cyberkinetics Neurotechnology Systems, Inc.
		CENTRAL INDEX KEY:			0001180253
		STANDARD INDUSTRIAL CLASSIFICATION:	SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
		IRS NUMBER:				134287300
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		SUITE 240
		STREET 2:		100 FOXBOROUGH BLVD.
		CITY:			FOXBOROUGH
		STATE:			MA
		ZIP:			02035
		BUSINESS PHONE:		508-549-9981

	MAIL ADDRESS:	
		STREET 1:		SUITE 240
		STREET 2:		100 FOXBOROUGH BLVD.
		CITY:			FOXBOROUGH
		STATE:			MA
		ZIP:			02035

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	TRAFALGAR VENTURES INC
		DATE OF NAME CHANGE:	20020814
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>form46472_030607142359-.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2007-03-02</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001180253</issuerCik>
        <issuerName>Cyberkinetics Neurotechnology Systems, Inc.</issuerName>
        <issuerTradingSymbol>CYKN.OB</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001304823</rptOwnerCik>
            <rptOwnerName>SURGENOR TIMOTHY R</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>100 FOXBOROUGH BLVD.</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 240</rptOwnerStreet2>
            <rptOwnerCity>FOXBOROUGH</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>US 02035</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>President and CEO</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2007-03-02</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>10000</value>
                    <footnoteId id="F1"/>
                </transactionShares>
                <transactionPricePerShare>
                    <value>1.13</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>10000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">The stock was awarded pursuant to the Fourth Amended and Restated 2002 Equity Incentive Plan as part of the 2006 annual bonus.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Timothy R. Surgenor</signatureName>
        <signatureDate>2007-03-06</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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