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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 HMXETFNnx7yrfgORpdsQdMcvCeqfAgxL02TXwdPTBk0d1rIU2JShiTkX/KkNk+Os
 /XLhOq4nMMzxXCogFGXuwQ==

<SEC-DOCUMENT>0001209191-06-038714.txt : 20060630
<SEC-HEADER>0001209191-06-038714.hdr.sgml : 20060630
<ACCEPTANCE-DATETIME>20060630121726
ACCESSION NUMBER:		0001209191-06-038714
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20060628
FILED AS OF DATE:		20060630
DATE AS OF CHANGE:		20060630

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			REPLIDYNE INC
		CENTRAL INDEX KEY:			0001180145
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000

	BUSINESS ADDRESS:	
		STREET 1:		1450 INFINITE DRIVE
		CITY:			LOUISVILLE
		STATE:			CO
		ZIP:			80027
		BUSINESS PHONE:		303-665-3450

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Christoffersen Ralph E
		CENTRAL INDEX KEY:			0001316252

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-52082
		FILM NUMBER:		06936384

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		303-417-1601

	MAIL ADDRESS:	
		STREET 1:		4430 ARAPAHOE AVENUE
		STREET 2:		SUITE 200
		CITY:			BOULDER
		STATE:			CO
		ZIP:			80303
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>bdn37209_bdn4rec.xml
<DESCRIPTION>MAIN DOCUMENT DESCRIPTION
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2006-06-28</periodOfReport>

    <issuer>
        <issuerCik>0001180145</issuerCik>
        <issuerName>REPLIDYNE INC</issuerName>
        <issuerTradingSymbol>RDYN</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001316252</rptOwnerCik>
            <rptOwnerName>Christoffersen Ralph E</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>MORGENTHALER VENTURES</rptOwnerStreet1>
            <rptOwnerStreet2>4430 ARAPAHOE AVENUE, SUITE 220</rptOwnerStreet2>
            <rptOwnerCity>BOULDER</rptOwnerCity>
            <rptOwnerState>CO</rptOwnerState>
            <rptOwnerZipCode>80303</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable></nonDerivativeTable>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Stock option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>10.00</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2006-06-28</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>16313</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <value>2006-06-28</value>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <value>2016-06-28</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>16313</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>16313</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">Automatic grant to Reporting Person of a stock option.  Option allows for early exercise and otherwise vests as follows:  33.33% of the shares vest one year after the date of grant with the remaining shares vesting thereafter in equal monthly installments over twenty-four months.  If early exercised, the shares purchased would be subject to reacquisition by the Issuer pursuant to the aforementioned vesting schedule.  The option expires ten years after the date of grant.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Ralph E. Christoffersen</signatureName>
        <signatureDate>2006-06-30</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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