Exhibit 99.16

December 3, 2008

Replidyne, Inc.
1450 Infinite Drive
Louisville, CO 80027

Consent to Reference in Proxy Statement/Prospectus

     In connection with the Registration Statement on Form S-4 filed by Replidyne, Inc. (the “Company”), filed on December 3, 2008, I hereby consent to the reference to me in the proxy statement/prospectus included in such registration statement as a future member of the board of directors of the Company.

Sincerely,

/s/ Gary M. Petrucci                                                           
Name: Gary M. Petrucci