X0202 4 2008-06-10 0 0001178879 AMICUS THERAPEUTICS INC FOLD 0001277478 SBLENDORIO GLENN C/O AMICUS THERAPEUTICS, INC. 6 CEDAR BROOK DRIVE CRANBURY NJ 08512 1 0 0 0 Stock Option (right to buy) 10.53 2008-06-10 4 A 0 10000 0.00 A 2018-06-10 Common Stock 10000 10000 D 1. One hundred percent of the shares subject to this option will vest and become exercisable on the date of the annual meeting of stockholders of the issuer to be held in 2009, provided that if the reporting person ceases to be a director of the issuer, this option shall cease to be exercisable in any respect not later than ninety (90) days following that event. /s/ Glenn Sblendorio 2008-06-10