Consolidated Statements of Operations - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2020	Sep. 30, 2019	Sep. 30, 2020	Sep. 30, 2019
Revenue:
Net product sales	$ 67,437	$ 48,768	$ 190,315	$ 126,944
Cost of goods sold	8,399	5,596	21,627	15,018
Gross profit	59,038	43,172	168,688	111,926
Operating expenses:
Research and development	70,419	58,892	229,150	194,466
Selling, general, and administrative	37,850	39,680	112,722	126,561
Changes in fair value of contingent consideration payable	1,034	789	2,680	2,652
Depreciation and amortization	2,496	1,116	6,299	3,261
Total operating expenses	111,799	100,477	350,851	326,940
Loss from operations	(52,761)	(57,305)	(182,163)	(215,014)
Other income (expense):
Interest income	518	2,752	2,898	7,990
Interest expense	(6,784)	(4,026)	(14,148)	(15,105)
Loss on exchange of convertible notes	0	0	0	(40,624)
Loss on extinguishment of debt	(7,276)	0	(7,276)	0
Other income (expense)	3,019	(3,481)	29	(3,272)
Loss before income tax	(63,284)	(62,060)	(200,660)	(266,025)
Income tax (expense) benefit	(727)	251	(4,791)	(634)
Net loss attributable to common stockholders	$ (64,011)	$ (61,809)	$ (205,451)	$ (266,659)
Net loss attributable to common stockholders per common share - basic and diluted (in dollars per share)	$ (0.25)	$ (0.24)	$ (0.80)	$ (1.13)
Weighted-average common shares outstanding - basic and diluted (in shares)	259,161,799	254,674,422	258,091,170	235,527,540