Consolidated Balance Sheets - USD ($) $ in Thousands	Mar. 31, 2020	Dec. 31, 2019
Current assets:
Cash and cash equivalents	$ 123,231	$ 142,837
Investments in marketable securities	215,642	309,903
Accounts receivable	40,555	33,284
Inventories	12,831	14,041
Prepaid expenses and other current assets	15,690	20,008
Total current assets	407,949	520,073
Operating lease right-of-use assets, less accumulated amortization of $6,260 and $5,342 at March 31, 2020 and December 31, 2019, respectively	32,501	33,315
Property and equipment, less accumulated depreciation of $19,260 and $17,604 at March 31, 2020 and December 31, 2019, respectively	47,688	47,705
In-process research & development	23,000	23,000
Goodwill	197,797	197,797
Other non-current assets	29,414	28,317
Total Assets	738,349	850,207
Current liabilities:
Accounts payable	16,239	21,722
Accrued expenses and other current liabilities	66,722	98,651
Deferred reimbursements	1,250	1,250
Operating lease liabilities	7,503	7,189
Total current liabilities	91,714	128,812
Deferred reimbursements	8,906	8,906
Convertible notes	2,167	2,131
Senior secured term loan	147,569	147,374
Contingent consideration payable	23,612	22,681
Deferred income taxes	5,051	5,051
Operating lease liabilities	52,522	53,531
Other non-current liabilities	4,214	5,296
Total liabilities	335,755	373,782
Commitments and contingencies
Stockholders’ equity:
Common stock, $0.01 par value, 500,000,000 shares authorized, 257,449,955 and 255,417,869 shares issued and outstanding at March 31, 2020 and December 31, 2019, respectively	2,607	2,598
Additional paid-in capital	2,238,346	2,227,225
Accumulated other comprehensive loss:
Foreign currency translation adjustment	6,981	2,785
Unrealized (loss) gain on available-for-sale securities	(169)	40
Warrants	12,387	12,387
Accumulated deficit	(1,857,558)	(1,768,610)
Total stockholders’ equity	402,594	476,425
Total Liabilities and Stockholders’ Equity	$ 738,349	$ 850,207