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Consolidated Balance Sheets (USD $)
In Thousands, unless otherwise specified
Mar. 31, 2015
Dec. 31, 2014
Current assets:    
Cash and cash equivalents $ 28,827us-gaap_CashAndCashEquivalentsAtCarryingValue $ 24,074us-gaap_CashAndCashEquivalentsAtCarryingValue
Investments in marketable securities 119,940us-gaap_AvailableForSaleSecuritiesCurrent 127,601us-gaap_AvailableForSaleSecuritiesCurrent
Prepaid expenses and other current assets 2,484us-gaap_OtherAssetsCurrent 2,902us-gaap_OtherAssetsCurrent
Total current assets 151,251us-gaap_AssetsCurrent 154,577us-gaap_AssetsCurrent
Available-for-sale Securities, Noncurrent 2,804us-gaap_AvailableForSaleSecuritiesNoncurrent 17,464us-gaap_AvailableForSaleSecuritiesNoncurrent
Property and equipment, less accumulated depreciation and amortization of $12,028 and $11,520 at March 31, 2015 and December 31, 2014 respectively 3,056us-gaap_PropertyPlantAndEquipmentNet 2,811us-gaap_PropertyPlantAndEquipmentNet
In-process research & development 23,000us-gaap_IntangibleAssetsNetExcludingGoodwill 23,000us-gaap_IntangibleAssetsNetExcludingGoodwill
Goodwill 11,613us-gaap_Goodwill 11,613us-gaap_Goodwill
Other non-current assets 892us-gaap_OtherAssetsNoncurrent 502us-gaap_OtherAssetsNoncurrent
Total Assets 192,616us-gaap_Assets 209,967us-gaap_Assets
Current liabilities:    
Accounts payable and accrued expenses 15,833us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent 16,345us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent
Current portion of secured loan 5,189us-gaap_SecuredDebtCurrent 3,840us-gaap_SecuredDebtCurrent
Total current liabilities 21,022us-gaap_LiabilitiesCurrent 20,185us-gaap_LiabilitiesCurrent
Deferred reimbursements 36,620us-gaap_DeferredCreditsAndOtherLiabilitiesNoncurrent 36,620us-gaap_DeferredCreditsAndOtherLiabilitiesNoncurrent
Secured loan, less current portion 9,208us-gaap_SecuredLongTermDebt 10,510us-gaap_SecuredLongTermDebt
Contingent consideration payable 11,700us-gaap_BusinessCombinationContingentConsiderationLiability 10,700us-gaap_BusinessCombinationContingentConsiderationLiability
Deferred tax liability 9,186us-gaap_DeferredTaxLiabilitiesGrossNoncurrent 9,186us-gaap_DeferredTaxLiabilitiesGrossNoncurrent
Other non-current liability 870us-gaap_OtherLiabilitiesNoncurrent 588us-gaap_OtherLiabilitiesNoncurrent
Commitments and contingencies      
Stockholders' equity:    
Common stock, $.01 par value, 125,000,000 shares authorized, 96,375,015 shares issued and outstanding at March 31, 2015 95,556,277 shares issued and outstanding at December 31, 2014 1,024us-gaap_CommonStockValue 1,015us-gaap_CommonStockValue
Additional paid-in capital 574,757us-gaap_AdditionalPaidInCapitalCommonStock 568,743us-gaap_AdditionalPaidInCapitalCommonStock
Accumulated other comprehensive income (35)us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax (132)us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax
Accumulated Deficit (471,736)us-gaap_RetainedEarningsAccumulatedDeficit (447,448)us-gaap_RetainedEarningsAccumulatedDeficit
Total stockholders' equity 104,010us-gaap_StockholdersEquity 122,178us-gaap_StockholdersEquity
Total Liabilities and Stockholders' Equity $ 192,616us-gaap_LiabilitiesAndStockholdersEquity $ 209,967us-gaap_LiabilitiesAndStockholdersEquity