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Employee Stock Options (Details) - Employee Stock Option [Member]
3 Months Ended 12 Months Ended
Mar. 31, 2019
Mar. 31, 2018
Dec. 31, 2018
Dec. 31, 2017
Summary of assumptions used to estimate fair value of stock options granted        
Expected dividend yield 0.00% 0.00% 0.00% 0.00%
Expected volatility 90.00%      
Risk-free interest rate   2.49%    
Expected life of options 4 years   4 years  
Minimum [Member]        
Summary of assumptions used to estimate fair value of stock options granted        
Expected volatility   83.00% 80.00% 82.00%
Risk-free interest rate 2.40%   2.41% 1.50%
Expected life of options   2 years 6 months   2 years 6 months
Maximum [Member]        
Summary of assumptions used to estimate fair value of stock options granted        
Expected volatility   86.00% 96.00% 101.00%
Risk-free interest rate 2.47%   2.93% 2.62%
Expected life of options   3 years   4 years