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Warrants (Tables) - Warrant [Member]
12 Months Ended
Dec. 31, 2016
Class of Warrant or Right [Line Items]  
Summarizes of the assumptions of estimate the fair value warrants granted

   2016  2015 
        
 Expected dividend yield  0% 0%
 Expected volatility  105 – 108% 116-121%
 Risk-free interest rate  .73 – .99% .87-1.70%
 Expected life of warrants  

1.4 – 3 years

  2.4 – 5 years
Schedule of warrant activity

   Number of Warrants  Weighted 
Average 
Exercise Price
  Weighted Average Remaining Contractual Life in Years  Aggregate Intrinsic 
Value
 
 Outstanding – December 31, 2014  12,129  $206.86   2.04     
 Exercisable – December 31, 2014  12,129  $206.86   2.04  $0.00 
 Granted  122,500  $6.53         
 Forfeited or Expired  (420) $250.35         
 Outstanding – December 31, 2015  134,209  $23.87   3.66     
 Exercisable – December 31, 2015  104,209  $27.87   4.01  $0.00 
 Granted  60,000  $2.91         
 Forfeited or Expired  (10,472) $193.72         
 Outstanding – December 31, 2016  183,737  $7.35   2.70     
 Exercisable – December 31, 2016  171,237  $7.15   2.79  $0.00