0001564590-18-023972.txt : 20181004 0001564590-18-023972.hdr.sgml : 20181004 20181004161522 ACCESSION NUMBER: 0001564590-18-023972 CONFORMED SUBMISSION TYPE: 8-K PUBLIC DOCUMENT COUNT: 6 CONFORMED PERIOD OF REPORT: 20181004 ITEM INFORMATION: Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers ITEM INFORMATION: Regulation FD Disclosure ITEM INFORMATION: Financial Statements and Exhibits FILED AS OF DATE: 20181004 DATE AS OF CHANGE: 20181004 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Paratek Pharmaceuticals, Inc. CENTRAL INDEX KEY: 0001178711 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 330960223 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 8-K SEC ACT: 1934 Act SEC FILE NUMBER: 001-36066 FILM NUMBER: 181108066 BUSINESS ADDRESS: STREET 1: 75 PARK PLAZA STREET 2: 4TH FLOOR CITY: BOSTON STATE: MA ZIP: 02116 BUSINESS PHONE: (617) 807-6600 MAIL ADDRESS: STREET 1: 75 PARK PLAZA STREET 2: 4TH FLOOR CITY: BOSTON STATE: MA ZIP: 02116 FORMER COMPANY: FORMER CONFORMED NAME: Transcept Pharmaceuticals Inc DATE OF NAME CHANGE: 20090130 FORMER COMPANY: FORMER CONFORMED NAME: NOVACEA INC DATE OF NAME CHANGE: 20020724 8-K 1 prtk-8k_20181004.htm 8-K prtk-8k_20181004.DOCX.htm

 

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d)

of the Securities Exchange Act of 1934

October 4, 2018

Date of Report (Date of earliest event reported)

PARATEK PHARMACEUTICALS, INC.

(Exact name of Registrant as specified in its charter)

 

 

 

 

 

Delaware

 

001-36066

 

33-0960223

(State or other jurisdiction

of incorporation)

 

(Commission

File Number)

 

(I.R.S. Employer

Identification No.)

 

 

75 Park Plaza

Boston, MA

 

02116

(Address of principal executive offices)

 

(Zip Code)

 

(617) 807-6600

(Registrant’s telephone number, including area code)

Not applicable

(Former name or former address, if changed since last report)

 

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

 

Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

 

Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

 

Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

 

Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

 

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (230.405 of this chapter) or Rule 12b-2of the Securities Exchange Act of 1934 (§ 240 12b-2 of this chapter).

 

Emerging Growth Company

 

If an emerging growth company, indicate by a check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act.

 

 


 


 

Item 5.02  Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

 

On October 4, 2018, Paratek Pharmaceuticals, Inc. (the “Company”) adopted the Revenue Performance Incentive Plan (the “Plan”) to grant performance-based cash incentive awards to key employees and consultants of the Company.  The Plan provides for an incentive pool of up to $50 million, plus accrued interest during the period between the awards’ vesting date and payment dates.  Each participant will be allocated a percentage of the incentive pool.

 

The incentive pool will be divided into two equal tranches with the first tranche vesting upon the Company’s achievement of cumulative product revenues over $300 million by December 31, 2025 (“Tranche 1”) and the second tranche vesting upon the Company’s achievement of cumulative product revenues over $600 million by December 31, 2026 (“Tranche 2”).  Participants will vest annually in each tranche of their awards in four equal installments on December 31, 2019, December 31, 2020, December 31, 2021, and December 31, 2022, subject to their continued employment with the Company through the applicable vesting date.  If a participant’s employment terminates prior to December 31, 2022 due to death or disability, the participant will automatically vest in an additional 25% of each tranche of his or her award.  Upon the achievement of a Tranche 1 or Tranche 2 milestone (but not a deemed achievement in connection with a change of control), each participant who has remained in continuous employment with the Company through December 31, 2022 will be 100% vested in the applicable tranche. In the event of a change of control of the Company prior to December 31, 2026, participants whose employment has terminated prior to such date will be eligible for payouts under the Plan based on the then-vested portion of their awards, and participants who have remained employed through the change of control will be deemed to have time vested in full in each tranche of their awards.

 

Upon the achievement of a Tranche 1 or Tranche 2 milestone (but not a deemed achievement in connection with a change of control), each participant’s payout in respect of the applicable tranche of his or her award will equal (a) the participant’s then-vested percentage, multiplied by (b) $25 million, multiplied by (c) the participant’s individual percentage allocation of the incentive pool.

 

If a change of control occurs prior to December 31, 2026, and the Tranche 1 milestone was not achieved prior to the change of control, the Tranche 1 milestone will be deemed to be achieved at a percentage equal to the greater of (1) 50% and (2) the cumulative product revenues as of the change of control, divided by $300 million.  If a change of control occurs prior to December 31, 2026, and the Tranche 2 milestone was not achieved prior to the change of control, the Tranche 2 milestone will be deemed to be achieved at a percentage equal to the greater of (1) 30% and (2) the cumulative product revenues as of the change of control, divided by $600 million.  A participant’s payout in respect of each tranche of his or her award in a change of control will equal (1) the participant’s then-vested percentage of such tranche, multiplied by (2) the percentage of that tranche’s milestone that has been achieved or is deemed to have been achieved, multiplied by (3) $25 million, multiplied by (4) the participant’s individual percentage allocation of the incentive pool.

 

Amounts that become payable upon achievement of the Tranche 1 milestone will be paid in a lump-sum in the first quarter of 2026, and amounts that become payable upon achievement of the Tranche 2 milestone will be paid in a lump-sum in the first quarter of 2027.  In the event of a change of control, any portion of the incentive pool that is earned, but unpaid, or deemed earned in connection with the change of control will be paid at the time of the change of control.

 

If a change of control occurs prior to the achievement of either or both of the Tranche 1 and Tranche 2 milestones, the awards will remain outstanding and the remaining unpaid portion of the incentive pool applicable to the Tranche 1 or Tranche 2 milestone, as applicable, will be paid following the achievement of either such milestone at the time or times the bonuses would otherwise be paid out.  Any successor in interest to the Company upon or following a change of control will be required to assume all obligations under the Plan.

 

Awards may be paid out in cash or in a combination of cash and registered securities of equal value (based on the Company’s 20-day trailing average closing price), with the portion paid in registered securities not to exceed 50% of the aggregate payment amount with respect to each tranche; provided, however, that any amounts payable with respect to an award in connection with a change in control will be paid in cash.

 

The foregoing is a description of the material terms of the Plan and is qualified by reference to the full text of the Plan and form of award under the Plan filed as Exhibits 10.1 and 10.2, respectively, to this Current Report on Form 8-K.

 

Item 7.01 Regulation FD Disclosure.

 

On October 4, 2018, the Company issued a press release announcing the acceptance of its submission to the European

 


 

Medicines Agency of the Marketing Authorization Application for omadacycline for the treatment of community-acquired bacterial pneumonia and acute skin and skin structure infections.

 

A copy of the press release is attached hereto as Exhibit 99.1 and is incorporated herein by reference.

 

Item 9.01 Financial Statements and Exhibits.

(d) Exhibits.

 


 


 

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

 

Date: October 4, 2018

 

 

 

PARATEK PHARMACEUTICALS, INC.

 

 

 

 

 

 

 

 

By:

 

/s/ William M. Haskel

 

 

 

 

 

 

 

 

 

 

Name: William M. Haskel

 

 

 

 

 

 

Title: Senior Vice President, General Counsel and Corporate Secretary

 

 

 

EX-10.1 2 prtk-ex101_6.htm EX-10.1 prtk-ex101_6.htm

Exhibit 10.1

PARATEK PHARMACEUTICALS, INC.

REVENUE PERFORMANCE INCENTIVE PLAN

 

1.DEFINED TERMS

Exhibit A, which is incorporated by reference, defines the terms used in the Plan and sets forth certain operational rules related to those terms.  

 

2.PURPOSE

The Plan has been established to provide awards to Participants from a revenue performance incentive pool based on U.S. sales of omadacycline.

 

3.ADMINISTRATION

The Administrator has discretionary authority, subject only to the express provisions of the Plan, to interpret the Plan; determine eligibility for and grant Awards, including the grant or reallocation of Awards following the forfeiture of previously granted Awards and, as appropriate, modifications to the vesting or payment terms of Awards to reflect any such additional grants or reallocations; determine, modify or waive the terms and conditions of any Award; prescribe forms, rules and procedures; and otherwise do all things necessary to carry out the purposes of the Plan.  Determinations of the Administrator made under the Plan will be conclusive and will bind all parties.

4.TYPE OF AWARDS

Each Award gives the holder thereof the conditional right to receive, subject to the provisions of the Plan and the Award, incentive payments based on a specified percentage of the Incentive Pool and the achievement of the performance goals set forth herein.  

5.ELIGIBILITY AND PARTICIPATION

The Administrator will select Participants from among those key employees and consultants of the Company and its subsidiaries who, in the opinion of the Administrator, are in a position to make a significant contribution to the success of the Company and its subsidiaries.

6.INCENTIVE POOL

An incentive pool (the “Incentive Pool”) will established under the Plan in an amount of up to $50 million, plus Accrued Interest, and will be divided into two tranches eligible to be earned based on the achievement of the following revenue milestones:

 

Tranche

Milestone

Pool Amount Payable

1

Cumulative Product Revenues over $300 million by December 31, 2025

$25 million, plus Accrued Interest

 


 

 

2

Cumulative Product Revenues over $600 million by December 31, 2026

$25 million, plus Accrued Interest

7.VESTING AND PAYMENT AMOUNTS

Participants will vest in each of Tranche 1 and Tranche 2 of their Awards in four equal annual installments as follows, subject to their remaining in continuous Employment through the applicable vesting date.

 

Vesting Date

Cumulative Percentage Vested and Payable upon Milestone Achievement

December 31, 2019

25%

December 31, 2020

50%

December 31, 2021

75%

December 31, 2022

100%

 

Notwithstanding the foregoing, in the event a Participant’s Employment terminates prior to December 31, 2022 due to the Participant’s death or Disability, the Participant will automatically vest on the date of his or her termination of Employment in an additional 25% of each tranche (i.e., the Participant will vest in that portion of each of Tranche 1 and Tranche 2 that would have otherwise vested in the year of such termination had the Participant remained in continuous Employment through December 31 of such year).

 

Upon the achievement of a Tranche 1 or Tranche 2 milestone (but not a deemed achievement in connection with a Change of Control), each Participant who has remained in continuous Employment through December 31, 2022 will be 100% vested in the applicable tranche payable by reason of the achievement of such milestone.  In such event, each Participant’s payout in respect of the applicable tranche of his or her Award will equal (a) the Participant’s then-vested percentage, multiplied by (b) $25 million, multiplied by (c) the Participant’s individual percentage allocation of the Incentive Pool.

 

8.CHANGE OF CONTROL

(a)In the event of a Change of Control on or prior to December 31, 2026:

(1)  Participants whose Employment has terminated prior to such date will be eligible for payouts as set forth below based on the then-vested portion of each tranche of their Awards; and

(2)  Participants who have remained in continuous Employment through the Change of Control will be deemed to have time vested in full in each tranche of their Awards and will be eligible for payouts as set forth below.

(b)If the Tranche 1 milestone was not achieved prior to the Change of Control, the

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Tranche 1 milestone will be deemed to be achieved at a percentage equal to the greater of (1) 50% and (2) the Cumulative Product Revenues as of the Change of Control, divided by $300 million.  

(c)If the Tranche 2 milestone was not achieved prior to the Change of Control, the Tranche 2 milestone will be deemed to be achieved at a percentage equal to the greater of (1) 30% and (2) the Cumulative Product Revenues as of the Change of Control, divided by $600 million.

(d)A Participant’s payout in respect of each tranche of his or her Award in a Change of Control will equal (1) the Participant’s then-vested percentage of such tranche, multiplied by (2) the percentage of that tranche’s milestone that has been achieved or is deemed to have been achieved, multiplied by (3) $25 million, multiplied by (4) the Participant’s individual percentage allocation of the Incentive Pool.

(e)If a Change of Control occurs prior to the achievement of either or both of the Tranche 1 and Tranche 2 milestones, the Awards shall remain outstanding and the remaining unpaid portion of the Incentive Pool applicable to the Tranche 1 or Tranche 2 milestone, as applicable, shall be paid following the achievement of either such milestone at the time or times set forth in Section 9 below.  Any successor in interest to the Company upon or following a Change of Control shall assume all obligations under the Plan, including but not limited to the obligation in the preceding sentence to keep Awards outstanding following the Change of Control.

 

9.TIMING OF PAYMENTS

Any amounts that become payable following achievement of the Tranche 1 milestone will be paid in a lump sum in the first quarter of 2026, and any amounts that become payable following achievement of the Tranche 2 milestone will be paid in a lump sum in the first quarter of 2027.  Notwithstanding the foregoing, in the event of a Change of Control, any portion of the Incentive Pool that is earned, but unpaid, or deemed earned in connection with the Change of Control will be paid at the time of the Change of Control.

 

10.FORM OF PAYMENT

Awards may be paid out in cash or in a combination of cash and registered securities of equal value (based on the Company’s 20-day trailing average closing price), with the portion paid in registered securities not to exceed 50% of the aggregate payment amount with respect to each tranche.  Notwithstanding the foregoing, in the event of a payment made at the time of a Change of Control, any amounts then payable with respect to an Award must be paid in cash.

 

11.RULES APPLICABLE TO AWARDS

(a)Award Provisions.  The Administrator will determine the terms of all Awards, subject to the limitations provided herein.  By accepting (or, under such rules as the Administrator may prescribe, being deemed to have accepted) an Award, the Participant shall be deemed to have agreed to the terms of the Award and the Plan.

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(b)Transferability.  No Awards may be transferred other than by will or by the laws of descent and distribution, subject to such limitations as the Administrator may impose.  In no event will transfer to a Person that the Administrator determines, directly or indirectly, provides services or financial or other support to a competitor of the Company be permitted.

(c)Taxes.  Payments under an Award shall be subject to and reduced by all applicable tax withholdings.

(d)Rights Limited.  Nothing in the Plan will be construed as giving any person the right to continued employment or service with the Company or its Affiliates.  The loss of existing or potential profit in Awards will not constitute an element of damages in the event of a Participant’s termination of Employment for any reason.

(e)Section 409A.  Each Award may contain such terms as the Administrator determines and shall be construed and administered to comply with the requirements of Section 409A.

12.AMENDMENT AND TERMINATION

The Administrator may at any time or times amend the Plan or any outstanding Award for any purpose which may at the time be permitted by law; provided that except as otherwise provided in an Award or in an employment or severance-benefit agreement applicable to the Participant, the Administrator may not, without the Participant’s consent, alter the terms of an Award so as to affect materially and adversely the Participant’s rights under the Award, unless the Administrator expressly reserved the right to do so at the time the Award was granted.

 

13.OTHER COMPENSATION ARRANGEMENTS

The existence of the Plan or the grant of any Award will not in any way affect the Company’s right to Award a person bonuses or other compensation in addition to Awards under the Plan.

 

14.MISCELLANEOUS

(a)Waiver of Jury Trial.  By accepting an Award under the Plan, each Participant waives any right to a trial by jury in any action, proceeding or counterclaim concerning any rights under the Plan and any Award, or under any amendment, waiver, consent, instrument, document or other agreement delivered or which in the future may be delivered in connection therewith, and agrees that any such action, proceedings or counterclaim shall be tried before a court and not before a jury.  By accepting an Award under the Plan, each Participant certifies that no officer, representative, or attorney of the Company has represented, expressly or otherwise, that the Company would not, in the event of any action, proceeding or counterclaim, seek to enforce the foregoing waivers.

(b)Limitation of Liability.  Notwithstanding anything to the contrary in the Plan,

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neither the Company, nor any Affiliate, nor the Administrator, nor any person acting on behalf of the Company, any Affiliate, or the Administrator, will be liable to any Participant or to the estate or beneficiary of any Participant or to any other holder of an Award by reason of any acceleration of income, or any additional tax (including any interest and penalties), asserted by reason of the failure of an Award to satisfy the requirements of Section 409A or by reason of Section 4999 of the Code, or otherwise asserted with respect to the Award.

15.ESTABLISHMENT OF SUB-PLANS

The Administrator may from time to time establish one or more sub-plans under the Plan for purposes of satisfying applicable blue sky, securities or tax laws of various jurisdictions.  The Administrator will establish such sub-plans by adopting supplements to the Plan setting forth (i) such limitations on the Administrator’s discretion under the Plan as the Administrator deems necessary or desirable and (ii) such additional terms and conditions not otherwise inconsistent with the Plan as the Administrator deems necessary or desirable.  All supplements adopted by the Administrator will be deemed to be part of the Plan, but each supplement will apply only to Participants within the affected jurisdiction and the Company will not be required to provide copies of any supplement to Participants in any jurisdiction that is not affected.

 

16.GOVERNING LAW

Except as otherwise provided by the express terms of an Award Agreement or under a sub-plan described in Section 15, the provisions of the Plan and of Awards under the Plan and all claims or disputes arising out of our based upon the Plan or any Award under the Plan or relating to the subject matter hereof or thereof will be governed by and construed in accordance with the domestic substantive laws of the State of Delaware without giving effect to any choice or conflict of laws provision or rule that would cause the application of the domestic substantive laws of any other jurisdiction.  By accepting an Award, each Participant will be deemed to (a) have submitted irrevocably and unconditionally to the jurisdiction of the federal and state courts located within the geographic boundaries of  the U.S. District Court for the District of Massachusetts for the purpose of any suit, action or other proceeding arising out of or based upon the Plan or any Award; (b) agree not to commence any suit, action or other proceeding arising out of or based upon the Plan or an Award, except in the federal and state courts located within the geographic boundaries of the U.S. District Court for the District of Massachusetts; and (c)  waive, and agree not to assert, by way of motion as a defense or otherwise, in any such suit, action or proceeding, any claim that it is not subject personally to the jurisdiction of the above-named courts that its property is exempt or immune from attachment or execution, that the suit, action or proceeding is brought in an inconvenient forum, that the venue of the suit, action or proceeding is improper or that the Plan or an Award or the subject matter thereof may not be enforced in or by such court.


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EXHIBIT A

 

Definition of Terms

 

The following terms, when used in the Plan, will have the meanings and be subject to the provisions set forth below:

 

“Accrued Interest”:  The accumulated interest on the incentive pool amount payable upon the achievement of a Tranche 1 or Tranche 2 milestone for each tranche during the Accumulation Period at LIBOR + 2% per year, compounded annually.

 

“Accumulation Period”:  For each tranche, the period beginning on the date the applicable Tranche 1 or Tranche 2 milestone is achieved and ending on the date that the Incentive Pool is paid out.

 

“Administrator”:  The Compensation Committee of the Board, except that the Compensation Committee may delegate (i) to one or more of its members such of its duties, powers and responsibilities as it may determine or (ii) to such officers of the Company or other persons as it determines such ministerial tasks as it deems appropriate.  In the event of any delegation described in the preceding sentence, the term “Administrator” will include the person or persons so delegated to the extent of such delegation.

 

“Affiliate”: With respect to any specified Person, any other Person which directly or indirectly through one or more intermediaries controls, or is controlled by, or is under common control with, such specified Person (for the purposes of this definition, “control” (including, with correlative meanings, the terms “controlling,” “controlled by” and “under common control with”), as used with respect to any Person, means the possession, directly or indirectly, of the power to direct or cause the direction of the management or policies of such Person, whether through the ownership of voting securities, by agreement or otherwise).

 

“Award”:  A right entitling a Participant to the payment of a percentage of the Incentive Pool set forth in his or her Award Agreement, subject to the vesting and service requirements set forth in the Plan and the other terms and conditions herein.

 

“Award Agreement”:  An agreement evidencing the grant of an Award under the Plan in the form of the agreement attached as Exhibit B hereto.

 

“Change of Control”:  Any of the following: (a) a merger or consolidation in which the Company is a constituent party (or if a subsidiary of the Company is a constituent party and the Company issues shares of its capital stock pursuant to such merger or consolidation), other than a merger or consolidation in which the voting securities of the Company outstanding immediately prior to such merger or consolidation continue to represent (either by remaining outstanding or by being converted into voting securities of the surviving entity) more than 50% of the combined voting power of the voting securities of the surviving entity outstanding immediately after such

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merger or consolidation, or (b) any transaction or series of related transactions in which in excess of 50% of the Company’s voting power is transferred, other than the sale by the Company of stock in transactions the primary purpose of which is to raise capital for the Company’s operations and activities, or (c) a sale, lease, exclusive license or other disposition of all or substantially all (as determined by the Board of Directors of the Company in its sole discretion) of the assets of the Company.

 

“Code”:  The U.S. Internal Revenue Code of 1986 as from time to time amended and in effect, or any successor statute as from time to time in effect.

 

“Company”:  Paratek Pharmaceuticals, Inc., a Delaware corporation, and its successors and assigns.

 

“Compensation Committee”:  The Compensation Committee of the Board of Directors of the Company.

 

“Combination Product”:  Any Product containing omadacycline and one or more other therapeutically active ingredients or as otherwise determined by the Compensation Committee with respect to other Products.

 

“Co-Promoter”:  Any Person that is not an Affiliate of the Company to whom the Company grants primarily (i.e. no other material rights to the Product are granted to such Person) the right to promote the Product in the Territory along with the Company and/or an Affiliate of the Company.

 

“Disability”:  With respect to a Participant, the inability of such Participant to engage in any substantial gainful activity by reason of any medically determinable physical or mental impairment that can be expected to result in death or that has lasted or can be expected to last for a continuous period of not less than twelve (12) months, as provided in Sections 22(e)(3) and 409A(a)(2)(c)(i) of the Code, and will be determined by the Board on the basis of such medical evidence as the Board deems warranted under the circumstances.

 

“Employment”:  A Participant’s employment or other service relationship with the Company and its subsidiaries.  Employment will be deemed to continue, unless the Administrator expressly provides otherwise, so long as the Participant is employed by, or otherwise is providing services to the Company or one of its subsidiaries and his or her employment or services have not permanently decreased to below 50% of the average level of services the Participant performed over the immediately preceding 36-month period.  If a Participant’s employment or services permanently decrease to between 20% and 50% of the average level of services he or she performed over the immediately preceding 36-month period, it will be in the discretion of the Administrator whether to treat such employment or service as continued employment or service under an Award.  Notwithstanding any of the foregoing, a Participant’s Employment will be deemed to terminate on his or her last day of actual and active employment or other service, and no period of notice or payment in lieu of notice that follows or is in respect of a period that follows

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the Participant’s last day of actual and active employment or other service will be deemed to extend his or her period of employment or service.  If a Participant’s employment or other service relationship is with a subsidiary and that entity ceases to be a subsidiary of the Company, the Participant’s Employment will be deemed to have terminated when the entity ceases to be a subsidiary of the Company unless the Participant transfers Employment to the Company or one of its remaining subsidiaries.

 

“License”:  An agreement in which the Company, its Affiliate or the Company’s Licensee grants or otherwise transfers any rights to commercialize the Product to a third party.

 

“Licensee”:  Any entity to which the Company, its Affiliate or the Company’s Licensee has granted a License.

 

“Net Sales”:  (a) With respect to a Product that is not a Combination Product, gross receipts from sales by the Company and its Affiliates, or Licensees or Co-Promoters of such Product to third parties in the Territory, less, in each case, (i) bad debts and (ii) sales returns and allowances actually paid, granted or accrued, including trade, quantity and cash discounts and any other adjustments, including those granted on account of price adjustments, billing errors, rejected goods, damaged or defective goods, recalls, returns, rebates, chargeback rebates, reimbursements or similar payments granted or given to wholesalers or other distributors, buying groups, health care insurance carriers, chain pharmacies, mass merchandisers, staff model HMOs, pharmacy benefit managers or other institutions, adjustments arising from consumer discount programs or other similar programs, customs or excise duties, sales tax, consumption tax,  value  added  tax,  and  other  taxes (except  income  taxes) or  dutiesrelating to sales, any payment in respect of sales to the United States government, any state government or any foreign government, or to any other governmental authority, or with respect to any government­ subsidized program or managed care organization, and freight and insurance; and (b) with respect to a Product that is a Combination Product, that percentage of Net Sales of such Combination Product (as determined in accordance with clause (a)) that relates to the Product as the Company may reasonably determine based on the wholesale acquisition costs of the Product and the other active ingredient(s) in such Combination Product when sold separately, or another similar approach.  Net Sales will be determined from the books and records of the Company and its Affiliates maintained in accordance with GAAP, as consistently applied by the Company with respect to sales of the Product.

 

“Participant”:  A person who is granted an Award under the Plan.

 

“Person”: Any individual, partnership, corporation, company, association, trust, joint venture, limited liability company, unincorporated organization, entity or division, or any government, governmental department or agency or political subdivision thereof.

 

“Plan”:  The Paratek Pharmaceuticals, Inc. Revenue Performance Incentive Plan, as from time to time amended and in effect.

 

“Product”:  Any Product that the Company (a)(1) owns and (2) sells, licenses as a licensor,

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or co-promotes, or (b)(1) does not own and (2) sells, licenses as a licensee, or co-promotes.

 

“Product Revenues”:  An amount equal to (a) 100% of Net Sales of the Product or appropriate percentage of a Combination Product in the Territory sold by the Company, any Licensee (other than a Co-Promoter) or any of their respective Affiliates, (b) 75% of Net Sales of the Product or appropriate percentage of a Combination Product in the Territory sold by any Co-Promoter, and (c) 100% of Net Sales of the Product or appropriate percentage of a Combination Product generated by the Company or any of its Affiliates as a co-promoter or licensee.  In the event the Company or any of its Affiliates receives non-cash consideration in connection with a License, the amount payable under clause (a) shall be calculated based on the fair market value of such consideration at the time of the transaction, assuming an arm’s length transaction made in the ordinary course of business.

 

“Section 409A”:  Section 409A of the Code.

 

“Territory”:  United States.

 


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EXHIBIT B

 

 

Form of Award Agreement

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EX-10.2 3 prtk-ex102_7.htm EX-10.2 prtk-ex102_7.htm

Exhibit 10.2

Name of Participant

[  ]

Percentage of Incentive Pool

[  ]

Grant Date

[  ]

 

PARATEK PHARMACEUTICALS, INC.

REVENUE PERFORMANCE INCENTIVE PLAN

 

AwARd AGREEMENT

 

THIS AWARD AGREEMENT (this “Award Agreement”), effective as of the grant date set forth above (the “Grant Date”), is made pursuant to the Paratek Pharmaceuticals, Inc. Revenue Performance Incentive Plan, as amended from time to time (the “Plan”), and is entered into by and between Paratek Pharmaceuticals, Inc., a Delaware corporation (the “Company”), and the individual whose name is set forth above (the “Participant”).  Unless otherwise specified, capitalized terms used in this Award Agreement but not otherwise defined herein shall have their respective meanings set forth in the Plan.

THE PARTIES HERETO AGREE AS FOLLOWS:

1.Award.  Pursuant to the Plan, the Company hereby grants to the Participant an award entitling the Participant to the percentage of the Incentive Pool specified above, subject to the terms and conditions set forth herein and in the Plan (the “Award”).

2.Expiration Date.  The Award, if not earlier forfeited, cancelled or otherwise terminated, will automatically terminate on December 31, 2026, and no amount will become payable in respect of the Award after such date other than any amounts payable in the first quarter of 2027 under Section 9 of the Plan following the achievement of the Tranche 2 milestone on or prior to December 31, 2026.

3.Binding Effect.  Subject to the limitations set forth in this Award Agreement and the Plan, this Award Agreement shall be binding upon, and inure to the benefit of, the executors, administrators, heirs, legal representatives, successors and assigns of the parties hereto.

4.Taxes.  

(a)Withholding.  The Participant expressly acknowledges and agrees that the Participant’s rights to receive any amounts payable hereunder will be reduced by such amounts as are required to satisfy withholding of all federal, state, local or other taxes required to be withheld, in each case, if any.

(b)Tax Advice.  The Participant expressly acknowledges and agrees that the Company has made no warranties or representations to the Participant with respect to the income tax consequences of the transactions contemplated by the Award, this Award Agreement, or the

 


 

Plan, and the Participant is in no manner relying on the Company or its representatives for an assessment of such tax consequences.

5.Successors and Assigns.  The rights, duties, and obligations under this Award Agreement and the Plan may not be assigned by the Participant and the Company, except that this Award Agreement shall be assignable by the Company to any successor entity, including an entity acquiring all, or substantially all, of the assets of the Company.  The provisions of this Award Agreement shall be binding on any such assignee.  

6.Entire Agreement; Amendments.  This Award Agreement and the Plan constitute the entire agreement among the parties with respect to the subject matter hereof and supersede all prior agreements, understandings, negotiations and discussions, whether oral or written, of the parties.  There are no agreements, understandings, specific restrictions, warranties, or representations relating to said subject matter between the parties other than those set forth herein or herein provided for.  In the event of any inconsistency between the Plan and this Award Agreement, the terms and conditions of this Award Agreement shall control.  This Award Agreement may be amended only in accordance with Section 12 of the Plan.

7.Waivers.  The failure of a party to insist upon strict performance of any provision of this Award Agreement in any one or more instances shall not be construed as a waiver or relinquishment of the right to insist upon strict compliance with such provision in the future.  In the event of any ambiguity in this Award Agreement or any matters as to which this Award Agreement is silent, the Plan will govern.

8.Invalidity.  In the event that any one or more of the provisions of this Award Agreement or any word, phrase, clause, sentence, or other portion thereof shall be deemed to be illegal or unenforceable for any reason, such provision or portion thereof shall be modified or deleted in such a manner so as to make this Award Agreement, as modified, legal and enforceable to the fullest extent permitted under applicable laws.

9.Governing Law.  The validity, construction and effect of this Award Agreement, and of any determinations or decisions made by the Administrator relating to this Award Agreement, and the rights of any and all Persons having, or claiming to have, any interest under this Award Agreement, shall be governed by and construed in accordance with the laws of the State of Delaware without regard to otherwise governing principles of conflicts of law.  Except as otherwise specified in an employment agreement between the Participant and the Employer, any suit with respect to this Award Agreement will be brought in the federal or state courts in the districts which include the State of Massachusetts, and the Participant agrees and submits to the personal jurisdiction and venue thereof.

10.Counterparts.  This Award Agreement may be executed in any number of counterparts, any of which may be executed and transmitted by facsimile (including “pdf”), and each of which shall be deemed to be an original, but all of which together shall be deemed to be one and the same instrument.

2

 

 


 

11.Further Representations and Acknowledgements of the Participant.

(a)The Participant hereby represents that he or she has read the Plan and is familiar with the Plan’s terms.  The Participant hereby acknowledges that he or she has carefully read this Award Agreement and agrees, on behalf of himself or herself and on behalf of his/her beneficiaries, estate and permitted assigns, to be bound by all of the provisions set forth herein and that the Award is subject to all of the terms and provisions of this Award Agreement and of the Plan, as each may be amended in accordance with its terms.  

(b)The Participant acknowledges that nothing in this Award Agreement alters the nature of his or her Employment with the Company.  The Participant acknowledges having been afforded a reasonable opportunity to consult with financial or legal advisors regarding the consequences of the Participant’s acceptance of the grant on the terms and conditions set forth in this Award Agreement.

 

[Remainder of the page intentionally left blank]

3

 

 


 

IN WITNESS WHEREOF, the parties hereto have executed this Award Agreement on the day and year first above written.

 

 

EX-99.1 4 prtk-ex991_8.htm EX-99.1 prtk-ex991_8.htm

                                                                                                                                                            Exhibit 99.1

 

 

Paratek Announces Acceptance of European Marketing Authorization Application for Oral and Intravenous Omadacycline

-- MAA submission for both community-acquired bacterial pneumonia (CABP) and acute bacterial skin and skin structure infections (ABSSSI) --

-- EMA decision expected second half of 2019 --

BOSTON, October 4, 2018 – Paratek Pharmaceuticals, Inc. (NASDAQ: PRTK) today announced the acceptance of the submission to the European Medicines Agency (EMA) of the Marketing Authorization Application (MAA) for omadacycline. Paratek is seeking approval of omadacycline, a modernized tetracycline, for the treatment of community-acquired bacterial pneumonia (CABP) and acute bacterial skin and skin structure infections (ABSSSI).  Omadacycline is a once-daily oral and intravenous (IV) broad spectrum antibiotic approved under the tradename NUZYRATM in the United States.  

The MAA is supported by the company’s Phase 3 program for omadacycline, which included three pivotal registration studies: two studies in ABSSSI and one study in CABP. Omadacycline met all required EMA primary endpoints in each study and demonstrated a generally safe and well-tolerated profile.

In the U.S., the FDA approved NUZYRA™ (omadacycline) in October 2018 for the treatment of adults with community-acquired bacterial pneumonia (CABP) and acute skin and skin structure infections (ABSSSI). 

About NUZYRA

 

NUZYRA (omadacycline) is a novel antibiotic with both once-daily intravenous (IV) and oral formulations for the treatment of community-acquired bacterial pneumonia (CABP) and acute bacterial skin and skin structure infections (ABSSSI). A modernized tetracycline, NUZYRA is specifically designed to overcome tetracycline resistance and exhibits activity across a spectrum of bacteria, including Gram-positive, Gram-negative, atypicals, and other drug-resistant strains.

 

Indications and Usage

 

NUZYRA™ is a tetracycline class antibacterial indicated for the treatment of adult patients with the following infections caused by susceptible microorganisms:

Community-Acquired Bacterial Pneumonia (CABP) caused by the following: Streptococcus pneumoniae, Staphylococcus aureus (methicillin-susceptible isolates), Haemophilus influenzae,

 


 

Haemophilus parainfluenzae, Klebsiella pneumoniae, Legionella pneumophila, Mycoplasma pneumoniae, and Chlamydophila pneumoniae.

 

Acute Bacterial Skin and Skin Structure Infections (ABSSSI) caused by the following: Staphylococcus aureus (methicillin-susceptible and -resistant isolates), Staphylococcus lugdunensis, Streptococcus pyogenes, Streptococcus anginosus grp. (includes S. anginosus, S. intermedius, and S. constellatus), Enterococcus faecalis, Enterobacter cloacae, and Klebsiella pneumoniae.  

 

Usage

To reduce the development of drug-resistant bacteria and maintain the effectiveness of NUZYRA and other antibacterial drugs, NUZYRA should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria.

 

Important Safety Information

 

Contraindications

NUZYRA is contraindicated in patients with known hypersensitivity to omadacycline or tetracycline class antibacterial drugs, or to any of the excipients.

 

Warnings and Precautions

Mortality imbalance was observed in the CABP clinical trial with eight deaths (2%) occurring in patients treated with NUZYRA compared to four deaths (1%) in patients treated with moxifloxacin.  The cause of the mortality imbalance has not been established. All deaths, in both treatment arms, occurred in patients > 65 years of age; most patients had multiple comorbidities.  The causes of death varied and included worsening and/or complications of infection and underlying conditions. Closely monitor clinical response to therapy in CABP patients, particularly in those at higher risk for mortality.

 

The use of NUZYRA during tooth development (last half of pregnancy, infancy and childhood to the age of 8 years) may cause permanent discoloration of the teeth (yellow-gray-brown) and enamel hypoplasia.

 

The use of NUZYRA during the second and third trimester of pregnancy, infancy and childhood up to the age of 8 years may cause reversible inhibition of bone growth.

 

Hypersensitivity reactions have been reported with NUZYRA. Life-threatening hypersensitivity (anaphylactic) reactions have been reported with other tetracycline-class antibacterial drugs.  NUZYRA is structurally similar to other tetracycline-class antibacterial drugs and is contraindicated in patients with known hypersensitivity to tetracycline-class antibacterial drugs. Discontinue NUZYRA if an allergic reaction occurs.

 

 


 

Clostridium difficile associated diarrhea (CDAD) has been reported with use of nearly all antibacterial agents and may range in severity from mild diarrhea to fatal colitis. Evaluate if diarrhea occurs.

 

NUZYRA is structurally similar to tetracycline-class of antibacterial drugs and may have similar adverse reactions. Adverse reactions including photosensitivity, pseudotumor cerebri, and anti-anabolic action which has led to increased BUN, azotemia, acidosis, hyperphosphatemia, pancreatitis, and abnormal liver function tests, have been reported for other tetracycline-class antibacterial drugs, and may occur with NUZYRA. Discontinue NUZYRA if any of these adverse reactions are suspected.

 

Prescribing NUZYRA in the absence of a proven or strongly suspected bacterial infection is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria.

 

Adverse Reactions

 

The most common adverse reactions (incidence ≥2%) are nausea, vomiting, infusion site reactions, alanine aminotransferase increased, aspartate aminotransferase increased, gamma-glutamyl transferase increased, hypertension, headache, diarrhea, insomnia, and constipation.

 

Drug Interactions

 

Patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage while taking NUZYRA.

 

Absorption of tetracyclines, including NUZYRA is impaired by antacids containing aluminum, calcium, or magnesium, bismuth subsalicylate and iron containing preparations.

 

Use in Specific Populations

 

Lactation: Breastfeeding is not recommended during treatment with NUZYRA.

 

To report SUSPECTED ADVERSE REACTIONS, contact Paratek Pharmaceuticals, Inc. at 1-833-727-2835 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

 

Please see full Prescribing Information for NUZYRA at www.NUZYRA.com.

 

About Paratek Pharmaceuticals, Inc.

 

Paratek Pharmaceuticals, Inc. is a biopharmaceutical company focused on the development and commercialization of innovative therapies based upon its expertise in novel tetracycline chemistry. The company’s lead commercial product, NUZYRA, is a once-daily intravenous and

 


 

oral antibiotic for the treatment of adult patients with community-acquired bacterial pneumonia and acute bacterial skin and skin structure infections. Paratek is also studying NUZYRA for the treatment of urinary tract infections (UTI).

 

Paratek has submitted a marketing authorization application for omadacycline in the European Union. Paratek has entered into a collaboration agreement with Zai Lab for the development and commercialization of omadacycline in the greater China region and retains all remaining global rights.

 

Under a research agreement with the U.S. Department of Defense, omadacycline also is being studied against pathogenic agents causing infectious diseases of public health and biodefense importance, including plague and anthrax.

 

Paratek’s second FDA approved product, SEYSARA™ (sarecycline), will be marketed by Almirall, SA in the U.S. as a new once-daily oral therapy for the treatment of acne. Paratek retains development and commercialization rights in the rest of the world.

 

Recognizing the serious threat of bacterial infections, Paratek is dedicated to providing solutions that enable positive outcomes and lead to better patient stories.

 

For more information, visit www.ParatekPharma.com or follow @ParatekPharma on Twitter.

 

Forward Looking Statements

 

This press release contains forward-looking statements, including statements about the development, launch and commercialization of NUZYRA, the potential for NUZYRA to treat ABSSSI, CABP, UTI and other serious community-acquired bacterial infections, the prospect of NUZYRA providing broad-spectrum activity and commercialization activities. All statements, other than statements of historical facts, included in this press release are forward-looking statements, and are identified by words such as “potential,” “prospective,” “prepare” and other words and terms of similar meaning. These forward-looking statements are based upon our current expectations and involve substantial risks and uncertainties. We may not actually achieve the plans, carry out the intentions or meet the expectations or projections disclosed in our forward-looking statements and you should not place undue reliance on these forward-looking statements. Our actual results and the timing of events could differ materially from those included in such forward-looking statements as a result of these risks and uncertainties. These and other risk factors are discussed under "Risk Factors" and elsewhere in our Annual Report on Form 10-K for the year ended December 31, 2017, and our other filings with the Securities and Exchange Commission. We expressly disclaim any obligation or undertaking to update or revise any forward-looking statements contained herein.  

 

PARATEK® and the Hexagon Logo are registered trademarks of Paratek Pharmaceuticals, Inc. NUZYRATM and its design logo are trademarks of Paratek Pharmaceuticals, Inc.

 


 

 

CONTACT:

 

 

 

Investor and Media Relations:

  

 

Ben Strain

  

 

617-807-6688

  

 

ir@ParatekPharma.com

  

 

 

 

 

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