Long-Term Debt - Summary of Debt (Detail) - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021	Apr. 30, 2018
4.75% Convertible Senior Subordinated Notes due 2024
Debt Instrument [Line Items]
Principal debt	$ 165,000	$ 165,000
Unamortized debt discount and issuance costs	(2,312)	(2,572)	$ (6,000)
Carrying value	162,688	162,428
R-Bridge Loan Agreement
Debt Instrument [Line Items]
Principal debt	60,000
Principal debt including paid-in-kind interest	61,918	61,256
Unamortized debt discount and issuance costs	(1,385)	(1,443)
Carrying value	60,533	59,813
Royalty Backed Loan Agreement
Debt Instrument [Line Items]
Principal debt including paid-in-kind interest	34,357	33,860
Unamortized debt discount and issuance costs	(1,629)	(1,673)
Carrying value	$ 32,728	$ 32,187